JACC:联合肺动脉压指导下治疗管理能明显改善心衰患者预后

2017-10-06 MedSci MedSci原创

对于心衰伴有射血分数降低(HFrEF)患者,尽管接受了指南指导下的治疗管理,住院率和死亡率依旧居高不下。对患者进行远程肺动脉压(PA)的监控有助于进一步改善治疗和预后。本研究纳入了550名慢性心衰的患者,并对HFrEF(左室射血分数≤40%)患者在肺动脉压指导下的治疗组和对照组之间预先通过亚分组分析比较其住院率和死亡率。在550名心衰患者中,其中有456名HFrEF患者,治疗组的心衰住院率要比对照

对于心衰伴有射血分数降低(HFrEF)患者,尽管接受了指南指导下的治疗管理,住院率和死亡率依旧居高不下。对患者进行远程肺动脉压(PA)的监控有助于进一步改善治疗和预后。本研究纳入了550名慢性心衰的患者,并对HFrEF(左室射血分数≤40%)患者在肺动脉压指导下的治疗组和对照组之间预先通过亚分组分析比较其住院率和死亡率。在550名心衰患者中,其中有456名HFrEF患者,治疗组的心衰住院率要比对照组低28%([HR]: 0.72; 95% [CI]: 0.59 - 0.88; p = 0.0013),死亡率要低32%(HR: 0.68; 95% CI: 0.45 - 1.02; p = 0.06)。有445名患者接受了至少一种指南指导下的药物治疗(ACEI、ARB或β受体阻滞剂),这些患者心衰住院率比对照组低33%(HR: 0.67; 95% CI: 0.54 - 0.82; p = 0.0002),死亡率低47%(HR: 0.63; 95% CI: 0.41 - 0.96, p = 0.0293)。此外,与对照组相比,接受了两种最佳治疗管理的患者住院率要低43%(HR: 0.57;

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    2018-08-04 hbwxf
  3. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfDEeydJz0GlP8O0ngrUX6AYCXFic0XDOOAyeQicIqnOd4TrWSwiagJrsFNYuWC1Uc6iavbS1hWt9xtZAhAqLGHqZyl/0, createdBy=42891977006, createdName=1e17414fm02(暂无匿称), createdTime=Sat Oct 07 00:38:58 CST 2017, time=2017-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250862, encodeId=bcb0250862b9, content=谢谢分享.学习受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Oct 06 16:59:08 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250826, encodeId=ba292508260c, content=肺动脉压监测下治疗心衰., beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Oct 06 14:26:36 CST 2017, time=2017-10-06, status=1, ipAttribution=)]
    2017-10-07 1e0e5697m83(暂无匿称)

    henhao

    0

  8. 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createdName=hbwxf, createdTime=Sat Aug 04 06:55:00 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1691931, encodeId=ca681691931af, content=<a href='/topic/show?id=a450530853c' target=_blank style='color:#2F92EE;'>#患者预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53085, encryptionId=a450530853c, topicName=患者预后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f4729287700, createdName=bnurmamat, createdTime=Tue Jun 12 00:55:00 CST 2018, time=2018-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325545, encodeId=d7ef1325545d8, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Oct 08 02:55:00 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373364, encodeId=097813e3364a1, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sun Oct 08 02:55:00 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1460684, encodeId=b284146068477, content=<a href='/topic/show?id=42a182045eb' target=_blank style='color:#2F92EE;'>#肺动脉压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82045, encryptionId=42a182045eb, topicName=肺动脉压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4b1e6357266, createdName=hxzhang, createdTime=Sun Oct 08 02:55:00 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251129, encodeId=4e04251129e1, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=b10c1938054, createdName=1e0e5697m83(暂无匿称), createdTime=Sat Oct 07 15:22:57 CST 2017, time=2017-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250960, encodeId=3581250960bd, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfDEeydJz0GlP8O0ngrUX6AYCXFic0XDOOAyeQicIqnOd4TrWSwiagJrsFNYuWC1Uc6iavbS1hWt9xtZAhAqLGHqZyl/0, createdBy=42891977006, createdName=1e17414fm02(暂无匿称), createdTime=Sat Oct 07 00:38:58 CST 2017, time=2017-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250862, encodeId=bcb0250862b9, content=谢谢分享.学习受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Oct 06 16:59:08 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250826, encodeId=ba292508260c, content=肺动脉压监测下治疗心衰., beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Oct 06 14:26:36 CST 2017, time=2017-10-06, status=1, ipAttribution=)]
    2017-10-07 1e17414fm02(暂无匿称)

    学习

    0

  9. 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encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sun Oct 08 02:55:00 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373364, encodeId=097813e3364a1, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sun Oct 08 02:55:00 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1460684, encodeId=b284146068477, content=<a href='/topic/show?id=42a182045eb' target=_blank style='color:#2F92EE;'>#肺动脉压#</a>, beContent=null, objectType=article, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfDEeydJz0GlP8O0ngrUX6AYCXFic0XDOOAyeQicIqnOd4TrWSwiagJrsFNYuWC1Uc6iavbS1hWt9xtZAhAqLGHqZyl/0, createdBy=42891977006, createdName=1e17414fm02(暂无匿称), createdTime=Sat Oct 07 00:38:58 CST 2017, time=2017-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250862, encodeId=bcb0250862b9, content=谢谢分享.学习受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Oct 06 16:59:08 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250826, encodeId=ba292508260c, content=肺动脉压监测下治疗心衰., beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Oct 06 14:26:36 CST 2017, time=2017-10-06, status=1, ipAttribution=)]
    2017-10-06 清风拂面

    谢谢分享.学习受益匪浅

    0

  10. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250826, encodeId=ba292508260c, content=肺动脉压监测下治疗心衰., beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Oct 06 14:26:36 CST 2017, time=2017-10-06, status=1, ipAttribution=)]
    2017-10-06 1e0f8808m18(暂无匿称)

    肺动脉压监测下治疗心衰.

    0

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