Eur Respir J:低风险肺栓塞患者右室扩张的预后价值!

2017-12-17 xing.T MedSci原创

由此可见,在sPESI为0的患者中,MDCT检查时RV/LV≥0.9和≥1.0较为常见,但与预后较差无关,这些患者中,较高的截止值可能与更加糟糕的结局相关。

多排螺旋CT(MDCT)在评估肺栓塞(PE)患者和简化肺栓塞严重程度指数(sPESI)为0的患者右心室扩张(RVD)中的预后价值尚不清楚。近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究析文章,研究人员探究了这些患者MDCT评估的RVD,由右心室与左心室比值来(RV/LV)≥0.9或≥1.0来定义,是否与不良预后相关。

研究人员结合了三个前瞻性队列研究的数据。该研究的主要结局为sPESI为0的患者30天的全因死亡、血流动力学崩溃或复发性PE。

在779例sPESI为0的患者中,分别有420例(54%)和299例(38%)患者RV/LV≥0.9和≥1.0。在主要研究终点之间研究人员未观察到显著差异,RV/LV≥0.9和≥1.0的患者分别为0.95%(95%可信区间为0.31-2.59) vs. 0.56%(95%可信区间为0.10-2.22;P=0.692)和1.34%(95%可信区间为0.43-3.62)和0.42%(95%可信区间为0.07-1.67;P=0.211)。将RV/LV的阈值增加至≥1.1,在RVD患者中结局发生更为常见(2.12%,95%可信区间为0.68-5.68 vs. 0.34%,95%可信区间为0.06-1.36;P=0.033)。

由此可见,在sPESI为0的患者中,MDCT检查时RV/LV≥0.9和≥1.0较为常见,但与预后较差无关,这些患者中,较高的截止值可能与更加糟糕的结局相关。

原始出处:

Benoit Côté,et al. Prognostic value of right ventricular dilatation in patients with low-risk pulmonary embolism. Eur Respir J. http://erj.ersjournals.com/content/50/6/1701611

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    2018-01-03 lsj637
  2. [GetPortalCommentsPageByObjectIdResponse(id=1684718, encodeId=f06f1684e18c7, content=<a href='/topic/show?id=794754e74f4' target=_blank style='color:#2F92EE;'>#扩张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54774, encryptionId=794754e74f4, topicName=扩张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=699d28086811, createdName=lsj637, createdTime=Wed Jan 03 16:39:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385202, encodeId=51261385202d7, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Tue Dec 19 13:39:00 CST 2017, time=2017-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=270337, encodeId=16ef2e03378c, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Dec 18 12:17:22 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=270289, encodeId=74e42e0289f3, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Mon Dec 18 08:43:03 CST 2017, time=2017-12-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1684718, encodeId=f06f1684e18c7, content=<a href='/topic/show?id=794754e74f4' target=_blank style='color:#2F92EE;'>#扩张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54774, encryptionId=794754e74f4, topicName=扩张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=699d28086811, createdName=lsj637, createdTime=Wed Jan 03 16:39:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385202, encodeId=51261385202d7, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Tue Dec 19 13:39:00 CST 2017, time=2017-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=270337, encodeId=16ef2e03378c, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Dec 18 12:17:22 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=270289, encodeId=74e42e0289f3, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Mon Dec 18 08:43:03 CST 2017, time=2017-12-18, status=1, ipAttribution=)]
    2017-12-18 清风拂面

    谢谢.学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1684718, encodeId=f06f1684e18c7, content=<a href='/topic/show?id=794754e74f4' target=_blank style='color:#2F92EE;'>#扩张#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54774, encryptionId=794754e74f4, topicName=扩张)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=699d28086811, createdName=lsj637, createdTime=Wed Jan 03 16:39:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1385202, encodeId=51261385202d7, content=<a href='/topic/show?id=dc121001e22d' target=_blank style='color:#2F92EE;'>#预后价值#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100172, encryptionId=dc121001e22d, topicName=预后价值)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=70fe497, createdName=paperyu, createdTime=Tue Dec 19 13:39:00 CST 2017, time=2017-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=270337, encodeId=16ef2e03378c, content=谢谢.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon Dec 18 12:17:22 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=270289, encodeId=74e42e0289f3, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Mon Dec 18 08:43:03 CST 2017, time=2017-12-18, status=1, ipAttribution=)]
    2017-12-18 天涯183

    非常好的文章.学习了

    0

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