体检出脂肪肝,怎么办?

2017-07-03 陈昭华 上海药训

体检出脂肪肝,怎么办?


脂肪肝!?是我太胖了吗?

脂肪肝又称脂肪性肝病。肝脏内有少许脂肪是正常的,但脂肪重量超过肝脏重量的5%~10%就形成脂肪肝。根据病因分为酒精性脂肪肝(ALD)和非酒精性脂肪肝(NAFLD)。

如果您有长期饮酒的习惯,很有可能是酒精性脂肪肝。若可排除病毒、药物、饮酒等原因引起的脂肪肝,非酒精性脂肪肝即可诊断。非酒精性脂肪肝又分为单纯性脂肪肝、脂肪性肝炎、脂肪性肝硬化,单纯性脂肪肝是各种肝毒性损伤的早期表现。

肥胖、高脂血症、2型糖尿病等单独或共同成为非酒精性脂肪肝的易感因素,在日常生活中应警惕。

但是,体型太瘦的人也可能得脂肪肝,因为营养摄入不能满足机体需要,体内缺少蛋白质和维生素,大量脂肪酸进入肝脏,导致肝内脂肪积蓄。

我平时没什么症状,血脂也只是轻度异常,肝功能正常,是不是不用治疗?

非酒精性脂肪肝起病隐匿,发病缓慢,并无症状。少数患者可有乏力、右上腹轻度不适、肝区隐痛或上腹痛等非特异性症状。常规体检部分患者可发现肝大。

毫无疑问,脂肪肝是需要治疗的,否则疾病很有可能进展,发展成为脂肪性肝炎和/或新发代谢紊乱及其相关并发症。轻症患者只需生活方式改变治疗+减肥(适于肥胖患者)±胰岛素增敏剂治疗。

除了彩超,还有其他的检查可以诊断脂肪肝吗?

超声检查是诊断脂肪肝重要而实用的手段,其诊断脂肪肝的准确率高达70%~80%左右。

CT是另一种影像学检查方法,另一项是病理学检查,肝活组织检查是诊断脂肪肝的“金标准”,可确认诊断,排除肝脏疾病其他不明原因,评估肝损伤程度及判断预后,但这是侵入性检查。

实验室检查,测定肝功能也是辅助诊断方法之一。

脂肪肝如何治疗?

非酒精性脂肪肝治疗的首要目标为控制代谢紊乱,防治糖尿病和心脑血管疾病。

饮食控制、增加运动量、修正不良行为等非药物治疗3~6月后,血压、血脂、血糖等代谢指标未能达到理想范围的脂肪肝患者,需及时使用相关药物,减少糖尿病和心脑血管疾病及其并发症的发生风险。并无特异性治疗脂肪肝的药物。

如需减肥,必要时可用二甲双胍等减肥药;

代谢综合征紊乱可选用胰岛素增敏剂(如二甲双胍、噻唑烷二酮类,适用于合并2型糖尿病的患者)和他汀类药物(适用于伴有总胆固醇、低密度脂蛋白升高的患者)或贝特类药物(适用于伴有明显甘油三酯升高的患者)治疗;

没有足够的证据支持,不建议给予成人患者omega-3脂肪酸治疗;

生化检查提示肝酶水平异常,可选择抗炎保肝药,如还原性谷胱甘肽、维生素E等。

脂肪肝需要长期治疗,由于肝组织病理学的变化普遍滞后于血液生化学指标的改善,故在生化指标改善后,不能立即停用抗炎保肝药。

听说降脂药有肝损作用,得了脂肪肝还能吃吗?

降脂治疗的目的是预防动脉硬化及急腹痛和胰腺炎(高甘油三酯血症),而不是为了减少肝脏脂肪沉积。服用他汀的患者应继续服用,但是3个月内若出现肝酶水平翻倍增高应考虑停药。

总而言之,如果体检出脂肪肝,应及时就医,明确脂肪肝类型。单纯性脂肪肝,可通过改变生活方式等使病情逆转甚至治愈;若效果不佳或病情进展,需在医生指导下规范用药

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    2017-07-05 marongnuan
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    2017-07-04 jiangxianchen

    中度脂肪肝的人飘过

    0

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    2017-07-04 lovezhenzhen13

    多运动没毛病

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1305108, encodeId=8dba130510850, content=<a href='/topic/show?id=ba392659e58' target=_blank style='color:#2F92EE;'>#体检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26597, encryptionId=ba392659e58, topicName=体检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b191324, createdName=marongnuan, createdTime=Wed Jul 05 11:37:00 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218619, encodeId=bf48218619d2, content=中度脂肪肝的人飘过, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuHfSLw3PzIKiaSnTBUuAtRkrrxWpibukl35iciaGtBq4LYQv4ian1tPC3IdmzWI2dZ3cDC8wUg5CnBxlJ/0, createdBy=33a51675735, createdName=jiangxianchen, createdTime=Tue Jul 04 23:11:53 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218570, encodeId=4b062185e03d, content=多运动没毛病, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9f651657781, createdName=lovezhenzhen13, createdTime=Tue Jul 04 18:43:32 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218452, encodeId=638d218452d8, content=现在瘦人检查出脂肪肝越来越常见,为什么, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Tue Jul 04 09:54:19 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218360, encodeId=88b42183607e, content=多谢分享……, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/23/8c541a9831aec7026dffdf6bf34ab45d.jpg, createdBy=11371963624, createdName=兰焱雨, createdTime=Tue Jul 04 06:49:40 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218333, encodeId=148d21833325, content=动起来比什么都重要!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2SEXGDldsNfP4rKvY7vJmaHcyvLXicuyaCTJtVOkX3jvd6DwNMD88hDjJwsU7MnUH6zeqC4zt3yGV/0, createdBy=4e701628585, createdName=flyingzyx, createdTime=Tue Jul 04 06:08:20 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218291, encodeId=762a21829195, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Tue Jul 04 00:11:54 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218285, encodeId=344521828525, content=这个没那么可怕吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Jul 04 00:10:19 CST 2017, time=2017-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218253, encodeId=ef972182539f, content=好好文学习了;, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon Jul 03 23:00:47 CST 2017, time=2017-07-03, status=1, ipAttribution=)]
    2017-07-04 lyh994

    现在瘦人检查出脂肪肝越来越常见,为什么

    0

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    2017-07-04 兰焱雨

    多谢分享……

    0

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    2017-07-04 flyingzyx

    动起来比什么都重要!

    0

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    2017-07-04 130****4638

    学习了受益匪浅

    0

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    2017-07-04 飛歌

    这个没那么可怕吧

    0

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    2017-07-03 139****5926

    好好文学习了;

    0

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