Stroke: 医院规模对美国儿童烟雾病预后的影响

2016-04-09 MedSci MedSci原创

背景:在美国有关儿童烟雾病治疗的综合多中心数据缺乏。研究者旨在识别儿童烟雾病诊断和治疗的趋势。方法:1997至2012期间,从儿童住院数据库中识别2454个烟雾病患者。对患者人口学资料,住院费用,干预措施及出院状态进行分析。将入院是否手术进行血运重建的患者进行分别分析。应用多元回归分析医院烟雾病的规模对预后的影响。结果:过去12年,烟雾病的治疗主要集中在高规模中心。在未进行手术血运重建的患者中,高

背景:在美国有关儿童烟雾病治疗的综合多中心数据缺乏。研究者旨在识别儿童烟雾病诊断和治疗的趋势。



方法:1997至2012期间,从儿童住院数据库中识别2454个烟雾病患者。对患者人口学资料,住院费用,干预措施及出院状态进行分析。将入院是否手术进行血运重建的患者进行分别分析。应用多元回归分析医院烟雾病的规模对预后的影响。

结果:过去12年,烟雾病的治疗主要集中在高规模中心。在未进行手术血运重建的患者中,高规模中心和低规模中心的患者住院时间,花费及并发症没有差异。但是,无血运重建的患者,小规模的医院非常规出院(OR,2.32;P = 0.0005)较多,住院死亡率较高(OR,12.7;P = 0.02)。相反,在进行手术血运重建的患者中,与低规模的中心相比,高规模中心的患者,住院时间(4.7 vs 6.2天,P= 0.004)减少,住院费用下降($88 000 vs $ 138 000;P<0.0001),并发症发生没有增加(P= 0.29)。进行血运重建的患者,入院到低规模比入院到高规模医院,非常规出院的可能性增加(OR 8.23; P=0.02)。

结论:这是目前为止,美国儿童烟雾病住院的最大研究。这些数据表明:医院规模与预后相关,高规模的中心能显著改善儿童烟雾病患者的治疗,降低死亡率,入院血运重建手术的患者有更显著的获益。

原文出处:

Titsworth WL, Scott RM, Smith ER. National Analysis of 2454 Pediatric Moyamoya Admissions and the Effect of Hospital Volume on Outcomes. Stroke. 2016 Apr 5.

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    2016-04-14 李继凯

    文章不错

    0

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    2016-04-14 李继凯

    值得学习

    0

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    2016-04-11 wei834766788

    好好看看学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1986787, encodeId=d4bf1986e876e, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Wed Dec 07 09:41:00 CST 2016, time=2016-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976784, encodeId=d3fa19e6784a1, content=<a href='/topic/show?id=e6e63560916' target=_blank style='color:#2F92EE;'>#医院规模#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35609, encryptionId=e6e63560916, topicName=医院规模)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Oct 14 03:41:00 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78128, encodeId=8c27e812814, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:33:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78129, encodeId=bfc1e81295a, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:33:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77329, encodeId=8054e732973, content=好好看看学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Mon Apr 11 00:43:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76645, encodeId=69cde66454a, content=需求决定研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Sun Apr 10 10:04:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76638, encodeId=4b61e663840, content=学习了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3bd31668701, createdName=1de07360m07(暂无匿称), createdTime=Sun Apr 10 07:24:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76636, encodeId=776ee663636, content=烟雾病确实对后期有很大影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzYWia0nMBiceOVIdKq3ibFKubbK7gTtfD7KAEnLB9zphibTvdpE2miaXQ7yVricG3ibiamDVnkia62xuDia998/0, createdBy=98b91706957, createdName=Wechatdb9b98ec, createdTime=Sun Apr 10 02:03:00 CST 2016, time=2016-04-10, status=1, ipAttribution=)]
    2016-04-10 lyh994

    需求决定研究

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1986787, encodeId=d4bf1986e876e, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Wed Dec 07 09:41:00 CST 2016, time=2016-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976784, encodeId=d3fa19e6784a1, content=<a href='/topic/show?id=e6e63560916' target=_blank style='color:#2F92EE;'>#医院规模#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35609, encryptionId=e6e63560916, topicName=医院规模)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Oct 14 03:41:00 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78128, encodeId=8c27e812814, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:33:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78129, encodeId=bfc1e81295a, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:33:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77329, encodeId=8054e732973, content=好好看看学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Mon Apr 11 00:43:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76645, encodeId=69cde66454a, content=需求决定研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Sun Apr 10 10:04:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76638, encodeId=4b61e663840, content=学习了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3bd31668701, createdName=1de07360m07(暂无匿称), createdTime=Sun Apr 10 07:24:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76636, encodeId=776ee663636, content=烟雾病确实对后期有很大影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzYWia0nMBiceOVIdKq3ibFKubbK7gTtfD7KAEnLB9zphibTvdpE2miaXQ7yVricG3ibiamDVnkia62xuDia998/0, createdBy=98b91706957, createdName=Wechatdb9b98ec, createdTime=Sun Apr 10 02:03:00 CST 2016, time=2016-04-10, status=1, ipAttribution=)]
    2016-04-10 1de07360m07(暂无匿称)

    学习了解

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1986787, encodeId=d4bf1986e876e, content=<a href='/topic/show?id=e21b2834245' target=_blank style='color:#2F92EE;'>#儿童烟雾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28342, encryptionId=e21b2834245, topicName=儿童烟雾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=568152, createdName=snowpeakxu, createdTime=Wed Dec 07 09:41:00 CST 2016, time=2016-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1976784, encodeId=d3fa19e6784a1, content=<a href='/topic/show?id=e6e63560916' target=_blank style='color:#2F92EE;'>#医院规模#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35609, encryptionId=e6e63560916, topicName=医院规模)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Fri Oct 14 03:41:00 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78128, encodeId=8c27e812814, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:33:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=78129, encodeId=bfc1e81295a, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=240a1683959, createdName=李继凯, createdTime=Thu Apr 14 18:33:00 CST 2016, time=2016-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77329, encodeId=8054e732973, content=好好看看学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=078f1661649, createdName=wei834766788, createdTime=Mon Apr 11 00:43:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76645, encodeId=69cde66454a, content=需求决定研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Sun Apr 10 10:04:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76638, encodeId=4b61e663840, content=学习了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3bd31668701, createdName=1de07360m07(暂无匿称), createdTime=Sun Apr 10 07:24:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=76636, encodeId=776ee663636, content=烟雾病确实对后期有很大影响, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzYWia0nMBiceOVIdKq3ibFKubbK7gTtfD7KAEnLB9zphibTvdpE2miaXQ7yVricG3ibiamDVnkia62xuDia998/0, createdBy=98b91706957, createdName=Wechatdb9b98ec, createdTime=Sun Apr 10 02:03:00 CST 2016, time=2016-04-10, status=1, ipAttribution=)]
    2016-04-10 Wechatdb9b98ec

    烟雾病确实对后期有很大影响

    0

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