遗传学研究揭示了骨关节炎新的治疗靶点

2019-01-28 MedSci MedSci原创

Sanger研究所、GSK及其合作者组成的研究小组发现了52种与骨关节炎相关的新的遗传变化,将与致残疾病相关的遗传区域扩大了一倍。该研究将为骨关节炎的新靶点的开发铺平道路。

Sanger研究所、GSK及其合作者组成的研究小组发现了52种与骨关节炎相关的新的遗传变化,将与致残疾病相关的遗传区域扩大了一倍。该研究将为骨关节炎的新靶点的开发铺平道路。

该研究一共分析了超过77000名骨关节炎患者和超过370000名健康人的全基因组,揭示了与骨关节炎相关的新基因和生物学途径,这不仅有助于开发骨关节炎的新药,还可以对现有药物进行评估。

骨关节炎是最普遍的肌肉骨骼疾病,并且是全世界残疾的主要原因。在英国,目前有近千万人患有骨关节炎,间接地导致每年的经济损失达148亿英镑。目前用于缓解该疾病疼痛的方法只能通过药物进行管理

Versus Arthritis研究主任Stephen Simpson博士评价说:"这项研究是了解骨关节炎复杂性和寻找新疗法的重要里程碑,我们很高兴为这项研究有所支持。从长远来看,这项研究在结束关节炎患者的疼痛的过程中取得了显着进展。"

原始出处:

http://www.pharmatimes.com/news/genetic_study_reveals_possible_newosteoarthritis_treatment_1275802

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    2019-05-29 lisa438
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    2019-01-30 lmm397
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    2019-01-29 lietome15

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

    0

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    2019-01-28 lietome2

    感谢小编为我们准备了如此丰盛的精神大餐,同时也向作者致谢!认真学习了,点赞!

    0

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