Pediatrics:多动症和神经兴奋剂不影响身高

2014-09-05 张乐 译 医学界儿科频道

此前对多动症、神经兴奋剂药物和成长之间关系的研究扑朔迷离。其中一些研究显示多动症儿童比正常儿童的身高要矮;一些研究也表明没有接受兴奋剂药物治疗的多动症儿童比同龄儿童否认身高要高。 根据在线发表于9月1日儿科学的研究显示,多动症以及用药物治疗多动症均对儿童的成长和身高没有影响。 为了更好地理解多动症以及多动症药物对儿童的身高的影响,Harstad博士和同事记录了明尼苏达州的41个公立和私立学校的

此前对多动症、神经兴奋剂药物和成长之间关系的研究扑朔迷离。其中一些研究显示多动症儿童比正常儿童的身高要矮;一些研究也表明没有接受兴奋剂药物治疗的多动症儿童比同龄儿童否认身高要高。[pdf free]


根据在线发表于9月1日儿科学的研究显示,多动症以及用药物治疗多动症均对儿童的成长和身高没有影响。

为了更好地理解多动症以及多动症药物对儿童的身高的影响,Harstad博士和同事记录了明尼苏达州的41个公立和私立学校的5718名儿童。其中,患有多动症的243名儿童的身高并不矮,对照组是具有相同年龄和性别的394名正常儿童。

来自马萨诸塞州波士顿儿童医院的Elizabetad和他的同事说: “此次研究显示神经兴奋药物治疗多动症和身高差异或增长变化并不相关。”

研究结果显示:

不管是多动症儿童与正常儿童做对比,还是服用兴奋药儿童与没有服用兴奋药物儿童做对比,他们的身高增长峰值速率(PHV)没有显著差异。

在患有多动症和没有患有多动症儿童之间,在测量成人身高的时候,他们并没有发现显著性的差别。男生的平均差异是-0.4cm(P=.56),女生平均差异是-1.1cm(P=.29)。

服用兴奋药物男生和没有服用兴奋药物男生的身高差异是0.6cm(P=.64),服用兴奋性药物和没有服用兴奋性药物女生之间差异是0.2cm.(P=.93)

研究者的确发现,PHV前使用神经兴奋剂的时间与PHV年龄存在正相关(r = 0.21; P = .01),但使用时长与成年期最终身高无关。

原始出处:

Harstad EB1, Weaver AL2, Katusic SK3, Colligan RC4, Kumar S5, Chan E1, Voigt RG6, Barbaresi WJ7.ADHD, Stimulant Treatment, and Growth: A Longitudinal Study.Pediatrics. 2014 Sep 1. pii: peds.2014-0428. [pdf free]


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    2015-03-20 hbwxf
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    2014-11-20 feather89
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    2014-11-27 cjyisheng

    解除患儿家长对患儿服药的顾虑。

    0

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    2014-09-07 lq1767

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