BMC Gastroenterol:补充益生菌可有效预防养老院老人抗生素相关腹泻的发生

2021-04-25 MedSci原创 MedSci原创

2-25%的养老院老人发生抗生素相关腹泻(AAD),可能会导致脱水、营养不良、严重并发症和住院。研究表明,益生菌可有效且安全的减少AAD。然而,在荷兰的疗养院中益生菌并没有常规使用。近日,研究人员制定

2-25%的养老院老人发生抗生素相关腹泻(AAD),可能会导致脱水、营养不良、严重并发症和住院。研究表明,益生菌可有效且安全的减少AAD。然而,在荷兰的疗养院中益生菌并没有常规使用。近日,研究人员制定了一个在养老院实施益生菌预防AAD的程序,以评估对AAD发生的影响,并评估益生菌在日常护理中的实施过程,研究结果已发表于BMC Gastroenterol。

研究人员采用PPE,在Rivas Zorggroep的三家疗养院为患有躯体和/或老年精神疾病的居民实施了益生菌管理。93名居民提供了167次使用抗生素的数据,其中84次包括补充益生菌,83次没有补充益生菌。在抗生素治疗开始时,每天服用两次多菌种益生菌,直到完成抗生素疗程后的1周。监测AAD的发生,并进行过程评估,以评估益生菌实施的促进因素和障碍。

 

结果显示,使用益生菌时,AAD的发作次数明显低于不使用益生菌时(20% vs 36%; p = 0,022, Chi-square)。在服用阿莫西林/克拉维酸或环丙沙星的老人中,没有发现AAD发生的明显差异。实施的促进因素是认为益生菌的好处和医务人员的处方。实施的阻碍是老人对益生菌的摄入量和个人决策哪些居民将从中受益。

综上所述,该研究结果表明,益生菌的成功实施可有效预防养老院老人AAD的发生。

 

原始出处:

 

Herman A van Wietmarschen, et al.,  Probiotics use for antibiotic-associated diarrhea: a pragmatic participatory evaluation in nursing homes. BMC Gastroenterol. 2020 May 13;20(1):151. doi: 10.1186/s12876-020-01297-w.

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    2021-11-02 许安
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    2021-05-04 我是谁是我

    学习了

    0

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    2021-04-27 tulenzi
  7. [GetPortalCommentsPageByObjectIdResponse(id=1975077, encodeId=566519e5077af, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Apr 06 21:23:56 CST 2022, time=2022-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1712785, encodeId=93f61e12785af, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Dec 30 07:23:56 CST 2021, time=2021-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2073320, encodeId=289e20e33200a, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Tue Nov 02 21:23:56 CST 2021, time=2021-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2065337, encodeId=8dd8206533ea1, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Fri Dec 03 09:23:56 CST 2021, time=2021-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=962543, encodeId=5cfa9625435d, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=73835475130, createdName=我是谁是我, createdTime=Tue May 04 06:04:16 CST 2021, time=2021-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1455521, encodeId=7f72145552156, content=<a href='/topic/show?id=1e35302e085' target=_blank style='color:#2F92EE;'>#养老院#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30270, encryptionId=1e35302e085, topicName=养老院)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f2715667301, createdName=tulenzi, createdTime=Tue Apr 27 14:23:56 CST 2021, time=2021-04-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960700, encodeId=39f3960e00bd, content=<a href='/topic/show?id=5d0ee2249b0' target=_blank style='color:#2F92EE;'>#益生菌#</a>有前途的, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72249, encryptionId=5d0ee2249b0, topicName=益生菌)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200529/3611e9bb629c4e5b81fbd8ce784b06cc/128487eae357460bb98f67d86230c218.jpg, createdBy=ab235268530, createdName=神盾医疗局局长Jack, createdTime=Mon Apr 26 18:22:25 CST 2021, time=2021-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=960597, encodeId=f32296059e31, content=<a href='/topic/show?id=5d0ee2249b0' target=_blank style='color:#2F92EE;'>#益生菌#</a>可有效预防养老院老人<a href='/topic/show?id=2838104142b7' target=_blank style='color:#2F92EE;'>#抗生素相关腹泻#</a>,事实上益生菌类型很多,还有一类真菌型益生菌,常规抗生素无法杀死它,这类益生菌用于抗生素相关腹泻,可能作用更独特!, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72249, encryptionId=5d0ee2249b0, topicName=益生菌), TopicDto(id=104142, encryptionId=2838104142b7, topicName=抗生素相关腹泻)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Mon Apr 26 12:39:52 CST 2021, time=2021-04-26, status=1, ipAttribution=)]
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    2021-04-26 小小医者

    #益生菌#可有效预防养老院老人#抗生素相关腹泻#,事实上益生菌类型很多,还有一类真菌型益生菌,常规抗生素无法杀死它,这类益生菌用于抗生素相关腹泻,可能作用更独特!

    0

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