J AAPOS.:儿童间歇性外斜视临床因素之间的关系

2017-07-02 cuiguizhong MedSci原创

在本项研究中,作者们确定了间歇性外斜视儿童立体视觉、外斜视控制与偏离角度之间的关系。虽然研究者们在立体视觉、控制和偏离角度之间发现了弱和中度的关联,但是孩子可以呈现立体视觉、控制和偏离角度的任何组合。

近日,来自美国得克萨斯州达拉斯西南视网膜基金会的Birch EE和加拿大魁北克蒙特利尔市中心医院大学Sainte-Justine大学的Superstein R等人在J AAPOS.杂志上发表了他们的最近研究:儿童间歇性外斜视临床因素之间的关系。

在本项研究中,作者们确定了间歇性外斜视儿童立体视觉、外斜视控制与偏离角度之间的关系。

研究收集了652名3-11岁的间歇性外斜视参与者的数据,这些参与者满足用于参加两项多中心随机临床试验之一的资格标准。他们依靠随机临床试验评估注册后立体视觉、对照和偏离角度之间的关系。

研究结果显示,任何水平的立体视觉和偏离角度都可以伴随任何水平的控制。距离立体视差较差(R = 0.26; 99%CI,0.17-0.36)和距离偏差角(R = 0.27; 99%CI,0.17-0.36)较差。邻近外斜视控制较差较弱,立体视差较差(R = 0.17; 99%CI,0.07-0.27),近距离偏角较大(R = 0.37; 99%CI,0.28-0.45)。在距离(R = 0.07; 99%CI,-0.03至0.17)或接近(R = 0.02; 99%CI,-0.08至0.12)的立体视差和偏离角度之间没有关联。

虽然研究者们在立体视觉、控制和偏离角度之间发现了弱和中度的关联,但是孩子可以呈现立体视觉、控制和偏离角度的任何组合。间歇性外斜视的诊断管理和发病机制中的控制、立体视觉和偏离角度的具体作用尚不清楚,似乎每个都产生一些独立的信息。

原文出处:

Superstein, R. et al. Relationship among clinical factors in childhood intermittent exotropia. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, doi:10.1016/j.jaapos.2017.04.005 (2017).

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    2018-05-07 ylz8410
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    2017-11-17 howi