Diabetes Care:NT-proBNP和hsTnT能否预测糖尿病患者微血管事件?(ADVANCE亚组研究)

2014-06-06 CMT 中国医学论坛报糖尿病手机报

大型降糖试验ADVANCE亚组研究显示,评估心脏生物标志物NT-proBNP和hsTnT可以适度改善对微血管事件的风险预测,文章5月30日在线发表于《糖尿病护理》(Diabetes Care)杂志。 研究纳入439例伴微血管事件的患者和2946例不伴微血管事件患者,检测其NT-proBNP和hsTnT水平。结果显示,NT-proBNP、hsTnT的对数转换值每增加1个标准差(SD),微血管事件风

大型降糖试验ADVANCE亚组研究显示,评估心脏生物标志物NT-proBNP和hsTnT可以适度改善对微血管事件的风险预测,文章5月30日在线发表于《糖尿病护理》(Diabetes Care)杂志。

研究纳入439例伴微血管事件的患者和2946例不伴微血管事件患者,检测其NT-proBNP和hsTnT水平。结果显示,NT-proBNP、hsTnT的对数转换值每增加1个标准差(SD),微血管事件风险比(HR)分别增加1.63和1.67。在风险预测模型中增加这两个指标可以改善糖尿病患者肾脏病变的预测,但对视网膜病变预测无影响。

原始出处:


Welsh P1, Woodward M2, Hillis GS2, Li Q2, Marre M3, Williams B4, Poulter N5, Ryan L6, Harrap S7, Patel A2, Chalmers J2, Sattar N8.Do Cardiac Biomarkers NT-proBNP and hsTnT Predict Microvascular Events in Patients With Type 2 Diabetes? Results From the ADVANCE Trial.Diabetes Care. 2014 May 30. pii: DC_132625. [Epub ahead of print]

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    2015-04-11 x35042875

    国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间

    0

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topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sun Jan 25 17:38:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636885, encodeId=22511636885e5, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed May 06 15:38:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759458, encodeId=79a01e5945802, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, 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style='color:#2F92EE;'>#NT-proBNP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13111, encryptionId=f6e513111bc, topicName=NT-proBNP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365287, encodeId=b742136528ecd, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473803, encodeId=53c014e380333, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=20804, encodeId=11ba208045b, content=国真实妊娠糖尿病患病率应该在这两种方案得到的患病率之间, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:47:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1643341, encodeId=c165164334183, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Tue 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likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Thu Sep 25 03:38:00 CST 2014, time=2014-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289286, encodeId=c9de12892864a, content=<a href='/topic/show?id=ede136018b' target=_blank style='color:#2F92EE;'>#BNP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3601, encryptionId=ede136018b, topicName=BNP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cd0d217, createdName=huiwelcome, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290327, encodeId=5a97129032e4f, content=<a href='/topic/show?id=f6e513111bc' target=_blank style='color:#2F92EE;'>#NT-proBNP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13111, encryptionId=f6e513111bc, topicName=NT-proBNP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365287, encodeId=b742136528ecd, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473803, encodeId=53c014e380333, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=)]
  6. 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topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Sun Jan 25 17:38:00 CST 2015, time=2015-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636885, encodeId=22511636885e5, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed May 06 15:38:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759458, encodeId=79a01e5945802, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Thu Sep 25 03:38:00 CST 2014, time=2014-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289286, encodeId=c9de12892864a, content=<a href='/topic/show?id=ede136018b' target=_blank style='color:#2F92EE;'>#BNP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3601, encryptionId=ede136018b, topicName=BNP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cd0d217, createdName=huiwelcome, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1290327, encodeId=5a97129032e4f, content=<a href='/topic/show?id=f6e513111bc' target=_blank style='color:#2F92EE;'>#NT-proBNP#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13111, encryptionId=f6e513111bc, topicName=NT-proBNP)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1365287, encodeId=b742136528ecd, content=<a href='/topic/show?id=2a2150e76fd' target=_blank style='color:#2F92EE;'>#微血管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50776, encryptionId=2a2150e76fd, topicName=微血管)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473803, encodeId=53c014e380333, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Jun 08 01:38:00 CST 2014, time=2014-06-08, status=1, ipAttribution=)]
    2014-09-25 智智灵药
  7. 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    2014-06-08 huiwelcome
  8. 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    2014-06-08 mjldent
  9. 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    2014-06-08 mgqwxj
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