BJU Int:根治性前列腺切除术前进行多参数核磁共振成像能够鉴定前列腺癌的导管内和筛状生长模式

2019-05-28 AlexYang MedSci原创

最近,有研究人员评估了根治性前列腺切除术前进行多参数前列腺核磁共振成像(MP-MRI)的诊断价值,目的是检测筛状结构(CA)与导管内前列腺癌(IDC)情况,这些最近被报道是不良的病理因素。研究包括了124名男性,他们在根治性前列腺切除前经历了MP-MRI。研究人员对他们的术前MP-MRI、前列腺切除组织学和临床跟踪调查细节进行了回顾。研究发现,根治性前列腺切除样本的病理学检查在124个案例中的89

最近,有研究人员评估了根治性前列腺切除术前进行多参数前列腺核磁共振成像(MP-MRI)的诊断价值,目的是检测筛状结构(CA)与导管内前列腺癌(IDC)情况,这些最近被报道是不良的病理因素。

研究包括了124名男性,他们在根治性前列腺切除前经历了MP-MRI。研究人员对他们的术前MP-MRI、前列腺切除组织学临床跟踪调查细节进行了回顾。研究发现,根治性前列腺切除样本的病理学检查在124个案例中的89个案例(71%)中鉴定了CA/IDC,MP-MRI鉴定了95个肿瘤中的86个具有CA/IDC,敏感度为90.5%(95%CI,82.8%-95.6%)。当比较病灶的位置时发现,PI-RADS分类与最高病理等级在124个案例中的106个案例中(85.5%)存在相关性。在2级病变患者组中,生化复发在31名CA/IDC患者中的11名中发生,而在21名不具有CA/IDC患者中的2名患者中发生。

最后,研究人员指出,MP-MRI在检测病理原发性前列腺癌中具有良好的敏感性,包括CA/IDC中的大部分案例。然而,具有CA/IDC的2级肿瘤患者对个体风险分层可靠的预测仍存在挑战。

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    2019-05-30 jeanqiuqiu
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    2019-05-28 misszhang

    前列腺癌相关研究,学习了,谢谢梅斯

    0

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