J Transl Med:空气污染会增加听力损失的风险么?

2021-10-30 AlexYang MedSci原创

评估了暴露于空气污染物居民发生突发性感音神经性听力损失的风险。

在过去十年中,空气污染已经成为一个重要的环境问题,特别是在发展中国家和发达国家。空气污染物的水平与人口密度、车辆排放、农业、工业排放、发电厂和化石燃料燃烧高度相关暴露在空气污染物中会引发全身性和特定组织炎症

目前,暴露于空气污染物与突发性感音神经性听力损失(SSNHL)之间的关系还没有广泛的调查。近期,有研究人员在《J Transl Med》上发表文章,评估了暴露于空气污染物居民发生突发性感音神经性听力损失的风险

研究人员在1998年至2010年期间招募了20岁以上无SSNHL病史的受试者,并对他们进行随访。空气质量数据由环境保护部门提供,并将1998年至2010年的PM2.5、SO2、CO、NO、NO2的年浓度按照梯度分为三个等级。研究人员计算了从基线到研究结束时的污染物年平均值,并将其分为三个等级。使用多变量Cox比例风险模型估计了调整后的风险比(aHR)。

研究结果发现,暴露于较高浓度的CO(aHR=2.16,95%CI 1.50-3.11)、NO(aHR=1.02,95%CI 1.01-1.03)和NO2(aHR=1.02,95%CI 1.01-1.04)的受试者发生SSNHL的风险明显升高。当把空气污染物浓度分为低、中、高三个水平,并选择低水平作为参考时,结果发现暴露于中水平(aHR=1.56,95%CI 1.20-2.04)或高水平(aHR=1.33,95%CI 1.01-1.75)的PM2.5的患者发生SSNHL的风险明显更高。

不同空气污染物浓度下,SSNHL的aHR情况

综上所述,长期暴露在空气污染中的居民患SSNHL的风险增加。然而,该研究结果仍需要进一步的试验和临床研究来验证。

原始出处:

Stella Chin-Shaw Tsai , Yi-Chao Hsu , Jung-Nien Lai et al. Long-term exposure to air pollution and the risk of developing sudden sensorineural hearing loss. J Transl Med. Oct 2021

 

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    2022-05-10 bsmagic9140
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    2021-11-01 ysjykql
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    2021-10-31 查查佳佳

    完善输注原则,优先选择ABO和RhD同型

    0

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