Ann Intern Med:简单扫描帮你确认15年内死亡风险

2015-07-07 佚名 生物谷

发表在最新Annals of Internal Medicine杂志上的一篇研究表示,冠状动脉钙化(CAC)扫描可以帮助医生确定病人是否有早卒的风险。 冠状动脉钙化扫描其实就是一个X射线断层摄影的测试,寻找冠状动脉壁上斑块聚集成的点。这些斑点被称为钙化,已经被认定为冠状动脉疾病的早期迹象。冠状动脉钙化的风险因子包括心脏病风险因子,血脂异常,高血压和肥胖等等。 来自Emory Universit

发表在最新Annals of Internal Medicine杂志上的一篇研究表示,冠状动脉钙化(CAC)扫描可以帮助医生确定病人是否有早卒的风险。

冠状动脉钙化扫描其实就是一个X射线断层摄影的测试,寻找冠状动脉壁上斑块聚集成的点。这些斑点被称为钙化,已经被认定为冠状动脉疾病的早期迹象。冠状动脉钙化的风险因子包括心脏病风险因子,血脂异常,高血压和肥胖等等。

来自Emory University医学院的心脏病学教授Leslee Shaw领导研究人员在1996年到1999年之间9715位研究参与者中收集并评估CAC评分和风险因素。大约有86%的参与者为白人,8%是非裔美国人,4%是西班牙裔美国人,2%是亚裔。这些参与者在门诊接受社区推广筛查项目的扫描,在扫描当时,患者并无任何冠状动脉疾病症状。

研究人员发现,评分准确地预测到了这些当时无症状患者在随后15年内的全因死亡率。整体15年的死亡率介于3%到28%,随着CAC评分在0到1000之间增加而增加。全因死亡率的相对危险性,在CAC评分在1至10之间是,只有1.68.而CAC评分达到1000甚至更高时,危险性达到6.26.因此作者认为CAC扫描可以帮助识别患者早卒的风险。

Shaw教授说:“这些发现使我们更好地了解冠状动脉钙化扫描的重要性—能够预测死亡率。高钙化分数的患者可能会被会建议采取更健康的生活方式,才能导致好的结果,并可能有助于延长他们的生命。”Shaw教授还表示CAC分数已经临床上被用来估计心血管疾病预后,和短期内各种原因下的死亡率,不过这项研究的分析了15年内的死亡率,这种长期分析是独一无二的。

原始出处

Shaw LJ, Giambrone AE, Blaha MJ, Knapper JT, Berman DS, Bellam N, Quyyumi A, Budoff MJ, Callister TQ, Min JK.Long-Term Prognosis After Coronary Artery Calcification Testing in Asymptomatic Patients: A Cohort Study.Ann Intern Med. 2015 Jul 7;
 

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    2015-07-09 保守主义

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    2015-07-09 保守主义

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    2015-07-08 huaxipanxing

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