Ocul Immunol Inflamm:口服抗结核药物治疗结核性泪囊炎的长期结果

2018-07-11 cuiguizhong MedSci原创

印度昌迪加尔医学教育与研究院眼科的Singh M近日在Ocul Immunol Inflamm发表一系列病例报告,描述了结核性泪腺炎(TbD)患者的临床放射学特征和长期预后情况。

印度昌迪加尔医学教育与研究院眼科的Singh M近日在Ocul Immunol Inflamm发表一系列病例报告,描述了结核性泪腺炎(TbD)患者的临床放射学特征和长期预后情况。

他们对接受彻底临床检查、眼眶成像研究和定制辅助检查的TbD患者进行回顾性观察研究。在某些情况下进行聚合酶链反应(PCR)和显微镜检查。使用4种药物联合抗结核的疗法(ATT),并且监测患者的临床反应。最低随访时间为6个月。

所有患者均为女性,3例患者出现疼痛、上睑下垂。总之,ESR升高,Mantoux测试为阳性,眼窝成像显示泪腺增大。在两名患者中观察到肉芽肿性炎症,PCR结果呈阳性。在平均17.25个月的随访中,所有女性都没有复发或临床复发的情况。

因此,作者认为,双侧泪腺增大,对ATT治疗的早期反应检测Mantoux和PCR时呈阳性,这些可为诊断TbD提供充分的证据。

原文出处:

Singh, M., et al., Long-Term Outcomes of Oral Anti-Tubercular Therapy in Patient with Tubercular Dacryoadenitis: A Case Series. Ocul Immunol Inflamm, 2018: p. 1-7.

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  5. 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  6. 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encodeId=a45c1254191a4, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Fri Jul 13 13:27:00 CST 2018, time=2018-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1454836, encodeId=c4da145483643, content=<a href='/topic/show?id=ca5f12e51d4' target=_blank style='color:#2F92EE;'>#NFL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12751, encryptionId=ca5f12e51d4, topicName=NFL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=90805606164, createdName=xiaoyeshuang, createdTime=Fri Jul 13 13:27:00 CST 2018, time=2018-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509901, encodeId=67d515099012b, content=<a href='/topic/show?id=d9d855612c2' target=_blank style='color:#2F92EE;'>#抗结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55612, encryptionId=d9d855612c2, topicName=抗结核)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c49410165177, createdName=wgx309, createdTime=Fri Jul 13 13:27:00 CST 2018, time=2018-07-13, status=1, ipAttribution=)]
    2019-01-21 lxg951
  7. 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    2018-07-13 xiaoyeshuang
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    2018-07-13 wgx309

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患者,男性,65岁。2年前体检发现空腹血糖9 mmol/L,未诊治。3月前查餐后血糖21 mmol/L,患者自觉多饮、多尿,自行服用二甲双胍500 mg bid,监测空腹血糖为13 mmol/L,餐后血糖17 mmol/L左右。曾自行加用阿卡波糖50 mg tid,因腹胀明显停用。现为优化降糖方案,评估并发症入院治疗。

口服型胰岛素

对于数百万患有1型糖尿病的人来说,每天一次或两次痛苦的针刺注射胰岛素是目前唯一的选择,因为他们的身体已经不能自行生产胰岛素。