Lancet Infect Dis:新加坡寨卡病毒防治经验

2017-05-18 zhangfan MedSci原创

寨卡病毒虽然可以传播蔓延,但疾病监测,媒介控制以及社会积极参与有助于迅速遏制病毒的进一步蔓延。新加坡的防控经验将有助于其他国家应对寨卡病毒的威胁

2016年8月寨卡病毒在新加坡爆发。近日研究人员公布了新加坡针对寨卡病毒感染爆发采取的国家响应措施。

在疫情爆发的第一阶段,疑似寨卡病毒感染患者被隔离直至血清检测结果呈阴性。增强的对疾病地区交通控制和社区管理,加强灭蚊效果和社区传染源控制,并与当地媒体合作提高疫情防控意识。在第二阶段,患者入院隔离停止但交通管控持续,开展疾病地区蚊子的物种、繁殖数量评估,并进行病毒测试。通过全基因组系统测序分析,比较蚊株与人类毒株的关系。

从2016年8月27日至11月30日,新加坡共确诊寨卡病毒感染455例,其中163名确诊患者在疫情爆发的第一阶段进行医院隔离,共97份血样以及157份尿液进行病毒检测。共有15个疫区,其中有12个疫区的埃及伊蚊繁殖率高,共对517个蚊子样本进行病毒筛查, 16个样本成阳性。在系统发育分析中,所有阳性蚊子均是共同的病毒携带蚊子的后代,与其他亚洲蚊子序列不同,大约在2016年5月蚊子开始携带寨卡病毒。通过交通和社区疾病控制,蚊子的繁殖率从7月至9月的3.62下降至9月至11月的1.22。

寨卡病毒虽然可以传播蔓延,但疾病监测,媒介控制以及社会积极参与有助于迅速遏制病毒的进一步蔓延。新加坡的防控经验将有助于其他国家应对寨卡病毒的威胁。

原始出处:


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    2018-03-04 howi
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    2017-05-19 虈亣靌

    不错的方式,努力学习,刻苦专研,不断总结出来新经验。

    0

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    2017-05-18 daiyaozu

    学习了,不错

    0

  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu May 18 16:08:06 CST 2017, time=2017-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=199627, encodeId=2e7a19962e6e, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Thu May 18 15:35:59 CST 2017, time=2017-05-18, status=1, ipAttribution=), 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    2017-05-18 Y—xianghai

    我们地方蚊子多了。

    0

  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Thu May 18 16:08:06 CST 2017, time=2017-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=199627, encodeId=2e7a19962e6e, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Thu May 18 15:35:59 CST 2017, time=2017-05-18, status=1, ipAttribution=), 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    2017-05-18 三生有幸9135

    学习一下谢谢分享

    0

  10. 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    2017-05-18 吴教授

    学习了

    0

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Cell:寨卡病毒能长期潜伏于神经系统和淋巴,可能造成其他疾病

研究结果表明,中枢神经系统中的持续性病毒可能有助于与Zika病毒感染相关的神经病变的产生。虽然Zika病毒通常在人体中引起轻度病状或无症状,但可能造成儿童和成人的神经系统疾病,如果感染的孕妇将病毒传染给胎儿,可能导致严重的胎儿缺陷,如小头症。但是,作者指出,如果Zika病毒可以持续在人类的中枢神经系统和其他组织中感染,那么可能会发生除了小头症以外的,更广泛的神经系统,淋巴,免疫疾病。

J Virol:武汉病毒所肖庚富研究组绘制寨卡病毒感染宿主细胞的蛋白应答图谱并发现候选药物

近期,国际病毒学领域权威学术期刊《Journalof Virology》在线发表了中国科学院武汉病毒研究所肖庚富研究团队在寨卡病毒(ZIKV)感染宿主细胞的定量蛋白质组学研究中取得重要进展,研究绘制了ZIKV感染宿主细胞后宿主蛋白的调控图谱,系统展示了ZIKV与宿主蛋白的相互作用情况。相关论文题为“Quantitative proteomic analysis of mosquito C6/36

JAMA Ophthalmol:寨卡病毒感染眼部病变临床表现

寨卡病毒感染眼部后遗症表现为局灶性色素斑,黄斑区脉络膜视网膜萎缩、先天性青光眼、视神经发育不全和视盘异常等

2017年4月14日Science期刊精华

图片来自Science期刊。2017年4月17日/生物谷BIOON/---本周又有一期新的Science期刊(2017年4月14日)发布,它有哪些精彩研究呢?让小编一一道来。 1.Science:先前的黄病毒感染会增强随后的寨卡病毒感染 doi:10.1126/science.aal4365 一种更加严重的登革热病毒(DENV)感染能够在之前接触过一种不同的DENV血清型的人

孕妇携带寨卡病毒,有 10% 几率生出先天性缺陷的孩子

美国疾病控制中心发布了一项新研究,详细介绍了寨卡病毒感染的孕妇的出生缺陷率,而且结果和我们担心的一样糟糕。

Nature:寨卡病毒助力蚊媒获得感染

蚊媒传染病是通过蚊虫叮咬传播给人类及动物宿主的一大类疾病。近年来,多种新发及再发病毒性蚊媒传染病,包括寨卡病毒(ZIKV)、登革病毒(DENV)和乙型脑炎病毒(JEV)等对人类的健康产生了严重的威胁。自1947年首先在乌干达发现以来,随后,ZIKV在法属波利尼西亚暴发,随即迅速蔓延至南美,引起了全球广泛关注。