血清铁蛋白检测临床意义

2022-01-04 厦门宝太生物 厦门宝太生物

铁蛋白是铁贮存的主要形式,在铁平衡中起重要作用。那么,血清铁蛋白检测临床意义又是什么?一文读懂!

铁蛋白是铁贮存的主要形式,在铁平衡中起重要作用。[1]铁蛋白是体内含铁最丰富的一种蛋白,在铁的代谢方面起着重要作用。血清铁蛋白能反映体内铁存储量及肌体的营养状态,是判定体内铁缺乏及铁负荷过大的有效指标。[2]

 

血清铁蛋白检测的临床应用 

 

婴幼儿及儿童缺铁性贫血

女性妊娠后月经停止,妊娠早期胎儿发育尚缓,缺铁性贫血较少发生,故早孕期和孕前差异不大。孕中期胎儿生长发育迅速,所需的营养素、微量元素矿物质也明显增多,尤其铁和钙,孕妇如不注意补充很容易出现铁缺乏和缺铁性贫血。[2]

《妊娠期缺铁和缺铁性贫血诊治指南》指出,铁蛋白是评估铁缺乏最有效和最容易获得指标。建议有条件的医疗机构对所有孕妇检测血清铁蛋白。

缺铁对儿童各个方面都会产生影响:

 

1

影响神经发育,缺铁会导致儿童反应变慢,严重的还会影响智力发育;

2

缺铁会导致淋巴细胞和白细胞受损,可能增加儿童被细菌感染的机率,容易发烧、感冒。

3

缺铁会使儿童容易感到疲惫,嗜睡。

4

消化能力下降,影响儿童生长发育。

 

血清铁蛋白在慢性肝病及肝癌中的检测

除了缺铁性贫血,铁蛋白还可作为肝病诊断的重要参考指标。研究结果显示,血清铁蛋白在肝癌组患者的水平明显高于健康组及慢性乙型肝炎、肝硬化组,且肝癌、肺癌、乳腺癌等恶性肿瘤均有体内铁蛋白增高的情况。[4]

 

 

铁蛋白的检测

血清铁蛋白是反应体内铁储备最具特异性的生化指标,当血清铁蛋白<30ng/ml时,表示体内铁元素耗尽早期,应及时补铁并进行治疗。

参考文献

[1]刘丽辉, 曹履先. 铁蛋白的临床应用[J]. 临床荟萃, 2011, 26(5):5.

[2]胡若愚, 叶飞, 詹乾钢,等. 血清铁蛋白检测的临床价值[J]. 中国误诊学杂志, 2001, 1(007):1089-1090.

[3]罗玉芳. 检测孕前及妊娠各期孕妇及其新生儿血清铁蛋白的意义[J]. 医学信息:中旬刊, 2011, 24(6):1.

[4]程玉萍.血清铁蛋白检查在临床应用的研究进展.山西医药杂志﹐2013,42:639-640.


 

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    2022-04-09 mnda
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    2022-01-08 ms1000001741405932

    学习

    0

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    2022-01-05 查查佳佳

    防治及用药的高度重视,HIV双药单一片剂

    0

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    2022-01-05 邹亮

    重要,实用,好好学习。

    0

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    2022-01-04 419040982

    很重要

    0

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    2022-01-04 ms7000001780120528

    记住了

    0

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