JAHA:传统心血管危险因素随着年龄增加反而“不危险”

2018-01-06 MedSci MedSci原创

目前,人们对心血管危险因素在不同年龄段对人体的影响尚未形成统一定论。本研究的目的旨在通过对一个队列进行长达40年的随访,观察心血管危险因素在不同年龄段对个体影响的变化。本研究在1970-1974年纳入了2322名男性,随访至2013年,并观察其心血管疾病结局情况。本研究在几个不同的年龄段:50,60,70,77和82岁对体重指数(BMI)、低密度脂蛋白和高密度脂蛋白胆固醇、甘油三酯、收缩压、舒张压

目前,人们对心血管危险因素在不同年龄段对人体的影响尚未形成统一定论。本研究的目的旨在通过对一个队列进行长达40年的随访,观察心血管危险因素在不同年龄段对个体影响的变化。

本研究在1970-1974年纳入了2322名男性,随访至2013年,并观察其心血管疾病结局情况。本研究在几个不同的年龄段:50,60,70,77和82岁对体重指数(BMI)、低密度脂蛋白和高密度脂蛋白胆固醇、甘油三酯、收缩压、舒张压、空腹血糖和吸烟情况进行全面评估分析,并将其与心肌梗死、缺血性卒中心衰进行关联分析。最终,年龄和传统心血管危险因素均与三个心血管结局呈相关性(p<0.05),此外,大多数传统心血管危险因素对疾病相关性随着年龄增加而降低,尤其是BMI与心梗的相关性、收缩压与缺血性卒中和心衰的相关性。在高龄人群中,低密度脂蛋白胆固醇仍与心梗的发生密切相关,BMI与空腹血糖与心衰的发生密切相关。

研究结果显示,传统心血管危险因素对疾病的影响随着年龄增加而降低,而某些因素在高龄人群中仍与心血管疾病密切相关。

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    2018-01-08 zhaohui6731
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    2018-01-06 changjiu

    学习一下谢谢

    0

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    2018-01-06 天地飞扬

    感觉没啥意义.五六十就出现高血压.高血糖.高血脂.长期吸烟的人也很少会活到八九十吧

    0

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    2018-01-06 天地飞扬

    学习了.谢谢分享!

    0

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    2018-01-06 方舒

    学习

    0

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