Arthritis res ther :RA患者关节术后MI风险更高!

2016-03-31 MedSci MedSci原创

近期发表在Arth Res Ther的一项回顾性队列研究称,关节术后,伴类风湿性关节炎(RA)的患者,其心肌梗死(MI)风险更高!研究者对240,571名患者,共计308,589次关节手术进行了数据分析,其中有3,654患者伴有RA。通过相关数据库识别患者的人口统计学和医疗相关信息,以及关节术后随访2年的情况。此外研究者还根据关节手术部位,将患者进行亚组分析(全髋关节置换术组和全膝关节置换术组)。

近期发表在Arth Res Ther的一项回顾性队列研究称,关节术后,伴类风湿性关节炎(RA)的患者,其心肌梗死(MI)风险更高!

研究者对240,571名患者,共计308,589次关节手术进行了数据分析,其中有3,654患者伴有RA。通过相关数据库识别患者的人口统计学和医疗相关信息,以及关节术后随访2年的情况。

此外研究者还根据关节手术部位,将患者进行亚组分析(全髋关节置换术组和全膝关节置换术组)。使用查尔森合并症指数对混杂因素进行校正。

总的来说,RA患者年龄更大,女性患者伴有更多的合并症,经济社会地位更低,不过吸烟比例更少。

研究数据显示,在关节术后第6周,其中伴有RA的患者其MI的校正后风险aOR=1.5;关节术后1年,MI的aOR=1.7,全因死亡风险OR=2.18,心血管事件死亡风险OR=2.3。

除全髋关节置换术和全膝关节置换术,与不伴RA的关节术后患者相比,RA患者术后6周和1年的MI风险更高。

原始出处:

Tropea J, et al. Higher risk for MI after joint surgery seen among patients with RA,Arthritis Res Ther. 2016;doi:10.1186/s13075-016-0958-5.

Higher risk for MI after joint surgery seen among patients with RA.Healio.March 30, 2016

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    2016-04-03 1de00086m73(暂无匿称)

    多学科治疗

    0

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    2016-04-02 zhaojie88
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    2016-03-31 milkshark

    新发现啊

    0

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    2016-03-31 milkshark

    值得推荐

    0

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