Eur Radiol:冠心病患者福音--通过冠脉CTA随访预测远期风险!

2017-11-02 shaosai MedSci原创

本研究旨在利用冠状动脉CT血管造影(CCTA)评价稳定性心绞痛患者冠状动脉粥样硬化斑块负荷进展的预测价值,并探究其与主要心血管事件(MACE)发生率的相关性,并将结果发表在Eur Radiol上。

本研究旨在利用冠状动脉CT血管造影(CCTA)评价稳定性心绞痛患者冠状动脉粥样硬化斑块负荷进展的预测价值,并探究其与主要心血管事件(MACE)发生率的相关性,并将结果发表在Eur Radiol上。本研究回顾性分析了有稳定性心绞痛病史并因心绞痛复发或加重多次进行CCTA检查的患者。定量分析冠状动脉斑块脂质核、纤维帽、钙化、整体斑块负荷及管径狭窄。通过随访来评价MACE发生率。本研究共纳入了268例患者(平均年龄52.9 ± 9.8岁,男性占71%),并对其进行了平均约4.6 ± 0.9年的随访。有富脂质、纤维化、钙化、整体斑块负荷(%)进展及冠状动脉管径狭窄(%)进展的患者MACE发生率要明显高于无上述进展的患者(p均 < 0.05)。富脂质斑块(HR = 1.601, p = 0.021)、整体斑块负荷(HR = 2.979, p = 0.043)和冠状动脉管径狭窄(HR = 4.327, p <0.001)是预测MACE的独立预测因子。本研究表明,发生心绞痛复发或其他症状加重的冠心病患者在CCTA图像上会有冠状动脉硬化进展,这会增加患者未来发生MACE的风险。原始出处:G

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    2018-08-10 windight
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    2017-11-04 许安

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