Anesth Analg:超声引导下腰方肌阻滞应用于剖宫产术后的镇痛效果

2018-02-11 田 磊 “罂粟花”微信号

罗哌卡因QL阻滞作为无椎管内吗啡用药多模式镇痛方案的一部分,可减少术后酚哌丙酮用量和疼痛强度。

背景与目的:传统定位和超声引导下腹横肌平面阻滞能降低剖宫产术后阿片类药物的用量。后路腰方肌阻滞 (QL)可为胸腰筋膜及椎旁间隙提供更好的局麻药扩散。本研究的目的是评价剖宫产后QL阻滞的效果。

方法:我们设计了这项随机、双盲、对照试验。40例剖宫产产妇术后接受双侧超声引导下分别用罗哌卡因2mg/ml或生理盐水行QL阻滞。所有患者均采用布比卡因联合舒芬太尼进行腰麻,并采用PCA泵内配有扑热息痛、布洛芬和酚哌丙酮的术后镇痛方案。记录不同剂量下的酚哌丙酮用量和给药时间。主要结局指标为术后24小时内酚哌丙酮用量。探索性分析比较了作为次要结局指标的反复测量的疼痛评分、恶心、疲劳以及直到病人能够站立和行走5米前的总时间差异及有效镇痛评分与时间的相互关系。

结果:40例患者均完成试验,每组20例。与对照组相比,2 4小时内累计酚哌丙酮用量降低(P=.04;均值比=0.60;95%置信区间,0.37-0.97)。与安慰剂组比较,治疗组在休息时(p<.01)和咳嗽(p<.01)时,镇痛效果明显优于安慰剂组(P<0.01)。

结论:罗哌卡因QL阻滞作为无椎管内吗啡用药多模式镇痛方案的一部分,可减少术后酚哌丙酮用量和疼痛强度。

原始出处:

Krohg A, Ullensvang K, Rosseland LA, Langester E, Sauter AR The Analgesic Effect of Ultrasound-Guided Quadratus Lumborum Block After Cesarean Delivery: A Randomized Clinical Trial   Anesth Analg. Feb,2018;126(2):559-565. doi: 10.1213/ANE.0000000000002648.

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    2018-08-26 AspirantSuo
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    2018-06-19 经常头晕
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  7. [GetPortalCommentsPageByObjectIdResponse(id=2051059, encodeId=4efc2051059ef, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Wed Jan 09 20:41:00 CST 2019, time=2019-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1813445, encodeId=9ffe181344577, content=<a href='/topic/show?id=0ba692e7473' target=_blank style='color:#2F92EE;'>#超声引#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92774, encryptionId=0ba692e7473, topicName=超声引)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb182500058, createdName=yuhaisheng_ibp_32061711, createdTime=Mon Dec 03 13:41:00 CST 2018, time=2018-12-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633448, encodeId=52fe1633448ff, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Sun Aug 26 04:41:00 CST 2018, time=2018-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1700063, encodeId=acf01e0006386, content=<a href='/topic/show?id=295524e541' target=_blank style='color:#2F92EE;'>#Anal#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2475, encryptionId=295524e541, topicName=Anal)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3a29999500, createdName=经常头晕, createdTime=Tue Jun 19 07:41:00 CST 2018, time=2018-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634681, encodeId=144f1634681ed, content=<a href='/topic/show?id=53e632e0970' target=_blank style='color:#2F92EE;'>#剖宫产术后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32709, encryptionId=53e632e0970, topicName=剖宫产术后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=5aed22248306, createdName=1249842em16(暂无昵称), createdTime=Sun Jul 15 21:41:00 CST 2018, time=2018-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769794, encodeId=51031e6979472, content=<a href='/topic/show?id=b3fc92e7516' target=_blank style='color:#2F92EE;'>#超声引导#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=92775, encryptionId=b3fc92e7516, topicName=超声引导)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d66e38113145, createdName=guoyibin, createdTime=Mon Jun 25 14:41:00 CST 2018, time=2018-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355269, encodeId=335f1355269bb, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon Feb 12 23:41:00 CST 2018, time=2018-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287030, encodeId=708c28e0305c, content=学习学习.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sun Feb 11 08:55:24 CST 2018, time=2018-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=287027, encodeId=63c628e0278a, content=优质资源.共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0LqDY57Aia0TOQByoJhNt3icm4sfukp500hLH6RHOpFdV01NbECtAV7s0qKpQPibyRukQAwAmqJU3X/0, createdBy=f91f1928792, createdName=九九消寒, createdTime=Sun Feb 11 08:49:05 CST 2018, time=2018-02-11, status=1, ipAttribution=)]
    2018-02-12 zhaojie88
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    2018-02-11 1dd8c52fm63(暂无匿称)

    学习学习.继续关注

    0

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    2018-02-11 九九消寒

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