Depress Anxiety：新退伍军人胃肠疾病与精神健康障碍有关

　　美国一项研究表明，在伊拉克战争和阿富汗战争的新退伍军人中，有精神健康障碍者的胃肠疾病（GID）患病率升高。成功检测和治疗与精神健康障碍相关的GID的需要初级卫生保健机构和精神卫生专科的共同努力。该研究论文3月14日在线发表于《抑郁与焦虑》（Depress Anxiety）杂志。

　　该研究是对退伍军人的健康记录的回顾性纵向队列分析。受试者为603221名伊拉克和阿富汗战争的退伍军人，他们为2001年10月7日（阿富汗战争开始）至2010年12月31日退伍军人医疗保健的新享有者。

　　结果显示，在新退伍军人中，GID的患病率近20％，并且有精神健康障碍的退伍军人患GID的概率至少是那些无精神健康障碍者的2倍。对于女性来说，患有抑郁症者GID患病风险升高最多。在男性中，那些伴有创伤后应激障碍者的肠易激综合征（IBS）患病风险升高最多。在两个性别中，IBS是与精神健康状况相关性最强的GID。

与胃肠相关的拓展阅读：

• FDA批准Stivarga治疗胃肠道间质瘤
• FDA批准瑞格非尼治疗晚期胃肠间质肿瘤
• J Clin Invest:胃肠癌症新疗法被发现
• J BACTERIOL:胃肠道细菌或有控制食欲作用
• NEJM：免疫功能低下患者诺如病毒胃肠炎的防治
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ASSOCIATION OF MENTAL HEALTH PROBLEMS WITH GASTROINTESTINAL DISORDERS IN IRAQ AND AFGHANISTAN VETERANS

Background

Gastrointestinal disorders (GIDs) represent a large public health burden, affecting an estimated 60–70 million Americans annually. Our goal was to examine the relationship between GID and the most common mental health disorders in a national group of newly returning veterans. We also evaluated gender differences in the association of mental health disorders and GID.

Methods

We utilized a retrospective, longitudinal cohort analysis of veterans’ health records. Participants were 603,221 Iraq and Afghanistan veterans who were new users of VA healthcare from October 7, 2001 (start of the war in Afghanistan) to December 31, 2010.

Results

The prevalence of GID in newly returning veterans was nearly 20%, and veterans with a mental health disorder were at least twice as likely to have a GID as those without mental health disorders. For women, the increased risk of all GIDs was greatest among those with depression. Among men, the increased risk of irritable bowel syndrome (IBS) was greatest among those with posttraumatic stress disorder. IBS was the GID most strongly associated with mental health conditions among both genders.

Conclusions

The large proportion of newly returning veterans with GIDs and comorbid mental health diagnoses is concerning. Successful detection and treatment of GIDs associated with mental health disorders will require integrated efforts from primary care and mental health.