CHEST指南和专家组报告-肺癌患者的咳嗽治疗

2017-01-22 MedSci MedSci原创

患有肺癌的患者出现咳嗽是常见症状,但通常没有得到治疗。近期,一项发表在Chest杂志上的研究使用了Cochrane系统评价以及其他证据来更新2006年CHEST指南关于这一主题的建议和建议。使用CHEST的方法学指南和建议、评估、开发和评估框架的分级方法。咳嗽专家组根据对Cochrane系统评价的主题、非对照研究、案例研究和临床的数据提出建议。根据德尔菲方法达成的最终分级。Cochrane系统综述

肺癌患者常常出现咳嗽,但通常没有得到治疗。

近期,一项发表在Chest杂志上的研究使用了Cochrane系统评价以及其他证据更新了2006年CHEST指南关于这一主题的建议和意见。

使用CHEST的方法学指南和建议、评估、开发和评估框架的分级方法。咳嗽专家组根据对Cochrane系统评价的主题、非对照研究、案例研究和临床的数据提出建议。根据德尔菲方法达成的最终分级。

Cochrane系统综述确定了17项主要低质量证据的试验。这些证据与非药物(止咳药)和药物治疗(缓和剂、阿片样物质、外周作用的镇咳药或局部麻醉剂)以及支气管内近距离放射治疗有关。

与2006年CHEST咳嗽指南相比,目前的意见和建议更具体,并采取了一种逐步的方法来治疗肺癌患者的咳嗽,承认该领域的低质量证据;迫切需要开发更有效的,通过高质量研究进行的循证干预。

原始出处:
Molassiotis A, Smith JA, Mazzone P, Blackhall F, Irwin RS; Chest Expert Cough Panel. Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer: CHEST Guidelines and Expert Panel Report.Chest. 2017 Jan 17. pii: S0012-3692(17)30022-3. 

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createdName=more is better!, createdTime=Sat Apr 15 13:49:00 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050585, encodeId=c4342050585f7, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sat Nov 18 13:49:00 CST 2017, time=2017-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1929272, encodeId=3c4819292e2ab, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Tue Dec 26 02:49:00 CST 2017, time=2017-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172478, encodeId=a0651e247862, content=采取了一种逐步的方法来治疗肺癌患者的咳嗽,承认该领域的低质量证据;迫切需要开发更有效的,通过高质量研究进行的循证干预。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Jan 25 08:47:01 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172199, encodeId=9de51e2199e6, content=很好,不错的指南,对我们极具指导作用。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 23 18:53:36 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172103, encodeId=1d2b1e210333, content=学习了,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:43:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172090, encodeId=b4da1e2090a5, content=好饿莫子好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:51 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172078, encodeId=d1d31e20786f, content=好文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Mon Jan 23 07:24:56 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172041, encodeId=3f9d1e2041c6, content=很好的学习资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161026/IMG58107C0F82E499574.jpg, createdBy=00e81970035, createdName=1e15b6fem30(暂无匿称), createdTime=Sun Jan 22 22:45:02 CST 2017, time=2017-01-22, status=1, ipAttribution=)]
    2017-12-26 Smile2680
  5. 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likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 23 18:53:36 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172103, encodeId=1d2b1e210333, content=学习了,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:43:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172090, encodeId=b4da1e2090a5, content=好饿莫子好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:51 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172078, encodeId=d1d31e20786f, content=好文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Mon Jan 23 07:24:56 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172041, encodeId=3f9d1e2041c6, content=很好的学习资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161026/IMG58107C0F82E499574.jpg, createdBy=00e81970035, createdName=1e15b6fem30(暂无匿称), createdTime=Sun Jan 22 22:45:02 CST 2017, time=2017-01-22, status=1, ipAttribution=)]
    2017-01-25 ylzr123

    采取了一种逐步的方法来治疗肺癌患者的咳嗽,承认该领域的低质量证据;迫切需要开发更有效的,通过高质量研究进行的循证干预。

    0

  6. 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encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Tue Dec 26 02:49:00 CST 2017, time=2017-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172478, encodeId=a0651e247862, content=采取了一种逐步的方法来治疗肺癌患者的咳嗽,承认该领域的低质量证据;迫切需要开发更有效的,通过高质量研究进行的循证干预。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Jan 25 08:47:01 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172199, encodeId=9de51e2199e6, content=很好,不错的指南,对我们极具指导作用。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 23 18:53:36 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172103, encodeId=1d2b1e210333, content=学习了,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:43:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172090, encodeId=b4da1e2090a5, content=好饿莫子好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:51 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172078, encodeId=d1d31e20786f, content=好文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Mon Jan 23 07:24:56 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172041, encodeId=3f9d1e2041c6, content=很好的学习资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161026/IMG58107C0F82E499574.jpg, createdBy=00e81970035, createdName=1e15b6fem30(暂无匿称), createdTime=Sun Jan 22 22:45:02 CST 2017, time=2017-01-22, status=1, ipAttribution=)]
    2017-01-23 ylzr123

    很好,不错的指南,对我们极具指导作用。点赞了!

    0

  7. 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encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Tue Dec 26 02:49:00 CST 2017, time=2017-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172478, encodeId=a0651e247862, content=采取了一种逐步的方法来治疗肺癌患者的咳嗽,承认该领域的低质量证据;迫切需要开发更有效的,通过高质量研究进行的循证干预。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Wed Jan 25 08:47:01 CST 2017, time=2017-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172199, encodeId=9de51e2199e6, content=很好,不错的指南,对我们极具指导作用。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 23 18:53:36 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172103, encodeId=1d2b1e210333, content=学习了,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:43:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172090, encodeId=b4da1e2090a5, content=好饿莫子好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:51 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172078, encodeId=d1d31e20786f, content=好文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Mon Jan 23 07:24:56 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172041, encodeId=3f9d1e2041c6, content=很好的学习资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161026/IMG58107C0F82E499574.jpg, createdBy=00e81970035, createdName=1e15b6fem30(暂无匿称), createdTime=Sun Jan 22 22:45:02 CST 2017, time=2017-01-22, status=1, ipAttribution=)]
    2017-01-23 wmu姿

    学习了,感谢分享

    0

  8. 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likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 23 18:53:36 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172103, encodeId=1d2b1e210333, content=学习了,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:43:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172090, encodeId=b4da1e2090a5, content=好饿莫子好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:51 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172078, encodeId=d1d31e20786f, content=好文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Mon Jan 23 07:24:56 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172041, encodeId=3f9d1e2041c6, content=很好的学习资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161026/IMG58107C0F82E499574.jpg, createdBy=00e81970035, createdName=1e15b6fem30(暂无匿称), createdTime=Sun Jan 22 22:45:02 CST 2017, time=2017-01-22, status=1, ipAttribution=)]
    2017-01-23 thlabcde

    好饿莫子好东西学习了!

    0

  9. 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likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 23 18:53:36 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172103, encodeId=1d2b1e210333, content=学习了,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:43:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172090, encodeId=b4da1e2090a5, content=好饿莫子好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:51 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172078, encodeId=d1d31e20786f, content=好文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Mon Jan 23 07:24:56 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172041, encodeId=3f9d1e2041c6, content=很好的学习资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161026/IMG58107C0F82E499574.jpg, createdBy=00e81970035, createdName=1e15b6fem30(暂无匿称), createdTime=Sun Jan 22 22:45:02 CST 2017, time=2017-01-22, status=1, ipAttribution=)]
    2017-01-23 1dd8aa01m06(暂无匿称)

    好文章,学习了

    0

  10. 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likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 23 18:53:36 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172103, encodeId=1d2b1e210333, content=学习了,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Mon Jan 23 09:43:49 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172090, encodeId=b4da1e2090a5, content=好饿莫子好东西学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:51 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172078, encodeId=d1d31e20786f, content=好文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Mon Jan 23 07:24:56 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172041, encodeId=3f9d1e2041c6, content=很好的学习资料。, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161026/IMG58107C0F82E499574.jpg, createdBy=00e81970035, createdName=1e15b6fem30(暂无匿称), createdTime=Sun Jan 22 22:45:02 CST 2017, time=2017-01-22, status=1, ipAttribution=)]
    2017-01-22 1e15b6fem30(暂无匿称)

    很好的学习资料。

    0

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上海市呼吸病研究所所长、复旦大学附属中山医院白春学教授介绍,全国肿瘤登记中心发布的《2015 年中国肿瘤登记年报》显示,我国 2011 年新增癌症病例 337.2万,癌症死亡病例 221.3万,全国恶性肿瘤发病率为 250.28/10万(男性 277.77/10万,女性 221.37/10万),中标率为 186.34/10万。其中肺癌发病率居于榜首。“中国肺癌发病率高、死亡率高,与吸烟关系密切。”

Peter Thiel押注的这家黑马公司,让40年没有进展的小细胞肺癌治疗,乍现希望

大约一周前,一个大学好友突然告诉我,他父亲被诊断为肺癌。他看我朋友圈都是些重磅进展,就问我是不是知道有效的治疗方法。在一番问候之后,我问他有没有让他父亲做基因检测,他说有这个打算。然后我让他赶紧带爸爸去做,同时给他说了一堆靶向治疗药物,以及Merck的Keytruda,和罗氏的Tecentriq。他沉默了一会儿,然后告诉我他父亲患的是晚期小细胞肺癌,已经出现耐药了。小细胞肺癌!为啥偏偏是小细胞

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portant; cursor: pointer; border-width: 0px; border-style: none; visibility: visible !important; width: 491px !important;">如果肺癌已经发生远处转移了,那么被治愈的希望非常渺茫。尽管如此,治疗可以帮助患者延长一段时间的生命和改善生活质量。放疗和化疗可以缩小肿瘤体积,减轻患者症状

JCO:精准化疗前路崎岖:ERCC1预测NSCLC铂类化疗结果不理想

与EGFR或ALK阳性的非小细胞肺癌(NSCLC)相比,无典型驱动基因突变的“野生型”NSCLC在过去10年间取得诊疗突破不多,绝大多数晚期患者只能选择含铂双药化疗。现在亟需的是能预测疗效的生物标志物,以指导优化为数不多的治疗选择。有希望成为含铂化疗生物标志物的是切除修复交叉互补组1(ERCC1)蛋白,ERCC1是核苷酸切除修复途径的重要成分,通过对铂类-DNA复合物的切除修复而影响铂类药物的疗效

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研究背景:SBRT已经成为不能耐受手术的早期非小细胞肺癌患者的一种标准治疗方案,2到3年的肿瘤局部控制率在93%到98%之间。通过肿瘤本身及治疗相关因素,可以预测其治疗的失败率,比如肿瘤大小和较低的放疗剂量。但是,非小细胞癌包括几种病理类型,不同病理类型是否影响治疗效果呢?方法:分析2003年至2015年符合条件的740例早期NSCLC患者,临床分期在T1N0M0 -T3N0M0,腺癌患者24