J Dairy Sci：乳制品中的特殊蛋白或可保护机体抵御心血管疾病

2015-06-16 佚名生物谷

美拉德反应是一种在复杂糖和氨基酸之间发生的褐变反应，当蛋白质和糖类混合在一起被加热时就会产生新的化合物，有些就会产生新的香料及其它物质，近日一篇发表在国家杂志Journal of Dairy Science上的研究论文中，来自高丽大学等处的研究人员就发现牛奶中的蛋白质可以帮助机体抵御心血管疾病的发生。文章中研究者表示，一种在乳制品中形成的饮食化合物可以降低小鼠机体血清中总的胆固醇水平、低密度脂

美拉德反应是一种在复杂糖和氨基酸之间发生的褐变反应，当蛋白质和糖类混合在一起被加热时就会产生新的化合物，有些就会产生新的香料及其它物质，近日一篇发表在国家杂志Journal of Dairy Science上的研究论文中，来自高丽大学等处的研究人员就发现牛奶中的蛋白质可以帮助机体抵御心血管疾病的发生。

文章中研究者表示，一种在乳制品中形成的饮食化合物可以降低小鼠机体血清中总的胆固醇水平、低密度脂蛋白（LDL）胆固醇的水平以及甘油三酯的水平，同时这些化合物也会像阿司匹林一样保护机体抵御急性肺血栓栓塞症，但并不会出现像阿司匹林疗法一样产生可能性的出血事件。

乳清蛋白浓缩物和酪蛋白酸钠同乳糖一起进行加热后就会产生乳清蛋白美拉德反应产物，随后乳酸菌就会利用其制造已经发酵的美拉德产物，而酪蛋白酸钠也会发生反应形成美拉德反应酪蛋白酸钠以及已经发酵的美拉德反应酪蛋白酸钠产物。

为了确定抗血栓药物的效果，研究者将60只小鼠分为四个治疗组，每组15只小鼠，第一组小鼠接受PBS，作为阴性对照组，第二组接受阿司匹林，作为阳性对照组，第三组接受乳清蛋白美拉德反应产物，第四组接受将发酵的美拉德产物同正常饮食进行搭配进行研究。同时研究者利用添加或不添加发酵的美拉德反应酪蛋白酸钠产物的多种饮食来对另外60只小鼠进行研究，来评估美拉德反应酪蛋白酸钠的抗氧化活性及降胆固醇效应。

结果研究者发现，美拉德反应产物及其发酵产物都可以降低动物模型的心血管疾病发病风险，另外研究者还指出，美拉德反应酪蛋白酸钠及其发酵产物应当被推荐作为抗氧化剂及保护心脏的制剂用于多种制药、功能性以及乳酪行业。本文研究或可帮助研究者理解乳制品对人类机体健康的额外价值，目前该研究仅在实验室对动物模型进行了研究，后期研究人员将对人类进行研究评估乳制品的产物对人类心血管健康的正向作用。

原始出处

N.S. Oh*, M.R. Park†, K.W. Lee†, S.H. Kim†, 1, , Y. Kim‡.et.al.Dietary Maillard reaction products and their fermented products reduce cardiovascular risk in an animal model .J Dairy Sci.2015

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2015-06-29 owlhealth

好的

114 0
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2015-06-25 huaxipanxing

看看

60 0
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2015-06-21 caierhong

很多国家的模式值得学习

114 0
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2015-06-21 caierhong

安全是个大问题

106 0
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2015-06-21 caierhong

监管部门不到位

103 0
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2015-06-18 andy2090

#血管疾病#

34 0
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2015-06-16 summer474cn

中国的可以吗？

94 0
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2015-06-16 summer474cn

中国食品药品安全问题存在隐患

83 0

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