Circulation:中国卒中患病率、发病率和死亡率分析

2017-01-06 xing.T MedSci原创

在中国脑卒中疾病负担比过去30年有所增加了,尤其是在农村地区,卒中负担特别重。脑卒中在中国有从北到南逐渐降低的梯度存在,卒中负担最大的地区是在北部和中部地区。

中国所拥有的卒中负担全世界最大。然而,目前全国层面的卒中患病率、发病率和死亡率以及过去30年的变化趋势尚不明确。近日,心血管领域权威期刊Circulation上专门针对这一问题发表了一篇研究文章。

2013年研究人员在中国31个省份155个城市和农村地区开展了能够代表全国的调查,共计调查了480,687名超过20岁的成年人,所有卒中幸存者在当时(2013年8月31日)被认为是卒中患病病例。第一次中风发生在调查点前一年内的患者被认为是卒中发病病例。根据CT、MRI或尸检发现,卒中分为缺血性卒中(IS)、脑出血(ICH)、蛛网膜下腔出血(SAH)和未定型脑卒中(UND)。

在480,687名参与者中,有7672名参与者被诊断为卒中患病(1596例每100,000人)和1643名参与者为卒中发病(345.1例每100,000人每年)。年龄标准化的患病率、发病率和死亡率分别为1114.8例每100,000人、246.8例和114.8例每100,000人每年。


90%的卒中患病病例和83%的卒中发病病例通过CT/MRI脑扫描确定了卒中的病理类型。在患病病例和发病病例之间,IS分别为69.6%和77.8%,ICH分别为23.8%和15.8%,SAH分别为4.4%和4.4%,UND分别为2.1%和2%。特定年龄的脑卒中患病率在超过40岁的男性显著高于女性(P<0.001)。

卒中幸存者中最常见的危险因素是高血压(88%)、吸烟(48%)和饮酒(44%)。在2013估计的脑卒中的患病率显著高于中国三十年前报道的患病率,尤其是农村居民中(P=0.017)。每年卒中发病率和死亡率最高的是东北地区(365例和159例每100,000人每年)、中部(326例和154例每100,000人每年);而卒中发病率最低的是西南地区(154例每100,000人每年);另外中国南方地区卒中的死亡率最低(65例每100,000人每年)(P<0.002)。

由此可见,在中国脑卒中疾病负担比过去30年有所增加,尤其是在农村地区,卒中负担特别重。脑卒中在中国有从北到南逐渐降低的梯度存在,卒中负担最大的地区是在北部和中部地区。

原始出处:

Wenzhi Wang, et al. Prevalence, Incidence and Mortality of Stroke in China: Results
from a Nationwide Population-Based Survey of 480,687 Adults
. Circulation.January 4, 2017.

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    2017-01-08 三生有幸9135

    脑卒中在中国有从北到南逐渐降低的梯度存在

    0

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    2017-01-07 Docteryuan

    不错,最近正在写关于动脉硬化的课题

    0

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    2017-01-06 李东泽

    很好,不错,以后会多学习

    0

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