IBD: 儿童回肠袋肛门吻合术后的短期和长期结果分析

2019-07-06 不详 MedSci原创

直肠结肠切除术、回肠肛管吻合术(IPAA)已成为溃疡性结肠炎或家族性腺瘤性息肉病恢复肠道连续性的首选方法。本系统评价旨在评估接受IPAA的儿科患者的短期术后和长期功能结果。

背景
直肠结肠切除术、回肠肛管吻合术(IPAA)已成为溃疡性结肠炎或家族性腺瘤性息肉病恢复肠道连续性的首选方法。本系统评价旨在评估接受IPAA的儿科患者的短期术后和长期功能结果。

方法
研究人员搜索了所有儿科IPAA的相关文献,数据收集包括患者人口统计学,术前药物使用,手术方法,术后30天结果,长期功能结果。对有或无围手术期皮质类固醇暴露的患者进行了比较。

结果
本项研究共纳入42份文献。<30天时浅表手术部位感染,盆腔败血症,肠梗阻和小肠梗阻的发生率分别为10%,11%,10%和14%。随访37-109个月,袋鞘,狭窄,慢性瘘管,尿失禁和小袋衰竭的发生率分别为30%,17%,12%,20%和8%; 术前暴露于皮质类固醇的患者尿失禁明显增多(52%vs 20%; P <0.001)。

结论
本项Meta分析指出IPAA是安全的,在儿科患者中具有良好的长期效果。

原始出处:

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    2019-08-22 hxj0127
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    2019-07-08 bnurmamat
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    2019-07-08 zhaojie88
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    2019-07-06 百草

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