一图读懂中国PD-1/PD-L1:2021.12

2021-12-28 e药安全 网络

一图读懂中国PD-1/PD-L1

2018.6月中国肿瘤免疫元年开启,至2021.12.12这短短3年半的时间

NMPA共批准了11款PD-1/PD-L1产品,涉及11个癌种44个适应症

预计2022年仍会有多款PD-1/PD-L1产品获批,例如基石、复宏、嘉和等

非小细胞肺癌:MSD、恒瑞,百济,信达均获批了鳞癌和腺癌一线,AZ巩固治疗独此一家。

小细胞肺癌:AZ和罗氏两家PD-L1作为唯二的一线。

肝癌:罗氏和信达均获批晚期一线治疗。

食管癌:MSD和恒瑞获批晚期一线治疗。

胃癌:O药为目前唯一晚期一线治疗。

鼻咽癌:恒瑞和君实领衔一线治疗。

头颈癌:MSD,BMS均在一线。

结直肠癌:MSD为目前唯一MSI-H一线治疗。

尿路上皮癌:君实和百济领先,但均为二线疗法。

黑色素瘤:K药和君实领先,均为二线治疗。

霍奇金淋巴瘤:最密集,多达5种。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1193404, encodeId=d74f11934041b, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78906503330, createdName=ms1000001353604776, createdTime=Mon Feb 14 20:55:55 CST 2022, time=2022-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1188046, encodeId=f081118804690, content=唉,PD-1治疗在卵巢癌中好像效果不太好, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d4015391287, createdName=尉明晶, createdTime=Tue Jan 25 15:54:33 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255131, encodeId=2925125513145, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Wed Dec 29 01:33:53 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085198, encodeId=788c10851985d, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d2ab5419366, createdName=xsybjmu, createdTime=Tue Dec 28 20:03:00 CST 2021, time=2021-12-28, status=1, ipAttribution=)]
    2022-02-14 ms1000001353604776

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1193404, encodeId=d74f11934041b, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78906503330, createdName=ms1000001353604776, createdTime=Mon Feb 14 20:55:55 CST 2022, time=2022-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1188046, encodeId=f081118804690, content=唉,PD-1治疗在卵巢癌中好像效果不太好, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d4015391287, createdName=尉明晶, createdTime=Tue Jan 25 15:54:33 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255131, encodeId=2925125513145, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Wed Dec 29 01:33:53 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085198, encodeId=788c10851985d, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d2ab5419366, createdName=xsybjmu, createdTime=Tue Dec 28 20:03:00 CST 2021, time=2021-12-28, status=1, ipAttribution=)]
    2022-01-25 尉明晶

    唉,PD-1治疗在卵巢癌中好像效果不太好

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1193404, encodeId=d74f11934041b, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78906503330, createdName=ms1000001353604776, createdTime=Mon Feb 14 20:55:55 CST 2022, time=2022-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1188046, encodeId=f081118804690, content=唉,PD-1治疗在卵巢癌中好像效果不太好, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d4015391287, createdName=尉明晶, createdTime=Tue Jan 25 15:54:33 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255131, encodeId=2925125513145, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Wed Dec 29 01:33:53 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085198, encodeId=788c10851985d, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d2ab5419366, createdName=xsybjmu, createdTime=Tue Dec 28 20:03:00 CST 2021, time=2021-12-28, status=1, ipAttribution=)]
    2021-12-29 smartjoy
  4. [GetPortalCommentsPageByObjectIdResponse(id=1193404, encodeId=d74f11934041b, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78906503330, createdName=ms1000001353604776, createdTime=Mon Feb 14 20:55:55 CST 2022, time=2022-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1188046, encodeId=f081118804690, content=唉,PD-1治疗在卵巢癌中好像效果不太好, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d4015391287, createdName=尉明晶, createdTime=Tue Jan 25 15:54:33 CST 2022, time=2022-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255131, encodeId=2925125513145, content=<a href='/topic/show?id=be71139214f' target=_blank style='color:#2F92EE;'>#PD-L1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13921, encryptionId=be71139214f, topicName=PD-L1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e76f39, createdName=smartjoy, createdTime=Wed Dec 29 01:33:53 CST 2021, time=2021-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1085198, encodeId=788c10851985d, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d2ab5419366, createdName=xsybjmu, createdTime=Tue Dec 28 20:03:00 CST 2021, time=2021-12-28, status=1, ipAttribution=)]
    2021-12-28 xsybjmu

    学习了!

    0

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