强生300亿美元收购欧洲很大生物制药公司Actelion 开辟罕见病治疗领域

2017-02-15 文倩玉 界面新闻

通过这笔交易,强生将在自身免疫疾病、心脏病、癌症等领域外,再度成为一个新疾病领域的领导者。



周四,强生同意宣布以300亿美元收购欧洲最大生物制药公司Actelion Pharmaceuticals,合每股280美元,高出周三收盘价23%。此外,收购后Actelion的研发部门将独立成为新的上市公司并转让给Actelion股东,强生则持有该公司16%的股份。



300亿美元的报价不仅刷新了强生的历史纪录,也大大高出近期同行业的收购水平。此前,辉瑞公司140亿美元收购前列腺癌制药商Medivation,艾伯维210亿美元收购抗癌生物技术公司Pharmacyclics。

这笔交易完成后,强生将获得Actelion旗下的Tracleer、Opsumit和Uptravi等治疗肺动脉高压的药物。此举将使其在自身免疫疾病、心脏病、癌症等领域外,再度成为一个新疾病领域的领导者。

成立于1997年的Actelion总部位于瑞士,由首席执行官Jean-Paul Clozel、其妻子Martine Clozel和原罗氏制药的数名科学家共同创办。十多年前,Tracleer的发现推动它成为治疗肺动脉高压的领导者。Uptravi和Opsumit紧随其后,并将取代面临专利失效的Tracleer。

作为公司最大股东,Clozel希望公司保持独立,因此他和他的妻子多年来一直抗拒收购竞标。现在Clozel将成为新拆分的研发公司的首席执行官。

在最初的持股16%的基础上,收购协议同时规定,强生通过可兑换票据可另行获得这一新公司16%的业务权,以及ACT-132577(一种针对抗高血压药物开发的产品)的选择权。

这桩破纪录的收购交易曾一度搁浅。去年11月强生宣布与Actelion就收购事宜进行初步磋商时对其估值约200亿美元。因在这一价格上无法达成交易,12月强生表示已放弃收购Actelion。另一制药巨头赛诺菲随即表示考虑对Actelion进行投标。但一星期后,强生重启收购谈判,并将估值提高到了300亿美元。

收购该公司将帮助强生公司进一步多样化药品种类和增加销售收入。目前,强生最主要的产品Remicade正面临来自辉瑞公司更廉价药品的竞争,而Actelion公司研发的抗罕见疾病药物一般都不会承受太多价格压力。

强生表示,这笔交易将在今年第二季度末完成,并将立即开始增加强生的收入。彭博社援引的分析师认为该交易将使强生长期利润率增长2%。

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    2017-02-17 syscxl
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喜讯!强生潜在重磅抗抑郁药艾氯胺酮(esketamine)斩获FDA第2个突破性药物资格

美国医药巨头强生(JNJ)在研抗抑郁药物艾氯胺酮(esketamine)近日在美国监管方面传来喜讯。FDA已授予esketamine治疗伴有紧迫自杀风险的重度抑郁症的突破性药物资格(BTD)。值得一提的是,此次BTD,也标志着esketamine在美国监管方面收获的第二个BTD。之前,FDA已于2013年11月授予esketamine治疗药物难治性抑郁症的突破性药物资格。 抑郁症是一种与自杀倾向

糖尿病重大喜讯!美国FDA批准强生复方新药Invokamet XR用于2型糖尿病一线治疗

美国医药巨头强生(JNJ)糖尿病管线近日在美国监管方面迎来重大喜讯。FDA已批准糖尿病复方新药Invokamet XR(canagliflozin/缓释二甲双胍),结合饮食和运动,用于2型糖尿病成人患者的一线治疗。Invokamet XR是由固定剂量的canagliflozin和缓释配方的二甲双胍组成的糖尿病复方药;canagliflozin(品牌名Invokana)是美国市场获批的首个也是处

强生为Darzalex申请新适应症,进军多发性骨髓瘤二线治疗

美国医药巨头强生(JNJ)近日宣布,向美国食品和药物管理局(FDA)提交肿瘤新药Darzalex(daratumumab)的补充生物制品许可(sBLA),寻求批准扩大该药当前的适应症,用于多发性骨髓瘤(MM)的二线治疗。具体而言,此次sBLA申请将Darzalex联合标准护理方案[lenalidomide(来那度胺,一种免疫调节剂)+地塞米松(dexamethasone,一种激素)]或[硼替佐

中国强生发布《2015年在华企业公民与可持续发展报告》

全球医疗保健行业的领先企业 -- 强生公司日前发布了《2015年强生在华企业公民与可持续发展报告》。报告彰显出强生在华积极响应国家在“十三五规划”中创新、协调、绿色、开放、共享的可持续发展理念,以及联合国推行可持续发展目标的要求。