JAHA:等待移植时的抑郁症与社会隔绝在心脏移植8年后生存率中的作用

2017-12-16 xiangting MedSci原创

等待移植时的低度抑郁和社会整合,与HTx 后的生存机会增加有关。

这项研究旨在探讨等待移植时评估的抑郁症和社会隔绝是否可以作为心脏移植(HT x)受体生存率的预测指标。

2005年至2006年间,318例成人HTx候选人被纳入Waiting for a New Heart研究,其中164例最终接受了移植。患者被随访至2013年2月。通过问卷评估其心理社会特征。欧洲国家器官储运组织提供患者在等待移植时的医疗数据、移植日期和供体特征;医院提供了HTx的医疗数据和HTx后的死亡日期。在中位随访70个月(HTx后<1-93个月),148例有完整数据的移植患者中56例(38%)死亡。抑郁评分与社会隔绝无关,与疾病严重程度也无关。更高的抑郁评分抬高了死亡风险(风险比= 1.07,95%置信区间,1.01,1.15,P = 0.032),而社会隔绝评分缓和了这种影响(显著交互作用;风险比= 0.985,95%置信区间, 0.973,0.998; P = 0.022)。在控制协变量的多变量模型中这些发现保持不变(P值为0.020-0.039)。等待移植时没有社会隔绝的低度抑郁症患者的1年/ 5年精确生存率最高(1年后86%,5年后79%)。抑郁或社会隔绝,或两者兼有的患者生存率较低,特别是移植后5年(分别为56%,60%和62%)。

等待移植时的低度抑郁和社会整合,与HTx 后的生存机会增加有关。这两个因素都应被考虑纳入对HTx候选人的标准化评估和干预。

原始出处:

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1801523, encodeId=3b2d1801523a2, content=<a href='/topic/show?id=a88be40248f' target=_blank style='color:#2F92EE;'>#社会隔绝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74024, encryptionId=a88be40248f, topicName=社会隔绝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f9279, createdName=slcumt, createdTime=Tue May 15 18:23:00 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256618, encodeId=4618125661846, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6a6043, createdName=guoyibin, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267654, encodeId=c35d126e65452, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616774, encodeId=20161616e7402, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269873, encodeId=3fc12698e37f, content=学习了.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Dec 16 15:25:37 CST 2017, time=2017-12-16, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1801523, encodeId=3b2d1801523a2, content=<a href='/topic/show?id=a88be40248f' target=_blank style='color:#2F92EE;'>#社会隔绝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74024, encryptionId=a88be40248f, topicName=社会隔绝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f9279, createdName=slcumt, createdTime=Tue May 15 18:23:00 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256618, encodeId=4618125661846, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6a6043, createdName=guoyibin, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267654, encodeId=c35d126e65452, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616774, encodeId=20161616e7402, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269873, encodeId=3fc12698e37f, content=学习了.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Dec 16 15:25:37 CST 2017, time=2017-12-16, status=1, ipAttribution=)]
    2017-12-18 guoyibin
  3. [GetPortalCommentsPageByObjectIdResponse(id=1801523, encodeId=3b2d1801523a2, content=<a href='/topic/show?id=a88be40248f' target=_blank style='color:#2F92EE;'>#社会隔绝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74024, encryptionId=a88be40248f, topicName=社会隔绝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f9279, createdName=slcumt, createdTime=Tue May 15 18:23:00 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256618, encodeId=4618125661846, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6a6043, createdName=guoyibin, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267654, encodeId=c35d126e65452, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616774, encodeId=20161616e7402, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269873, encodeId=3fc12698e37f, content=学习了.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Dec 16 15:25:37 CST 2017, time=2017-12-16, status=1, ipAttribution=)]
    2017-12-18 柳叶一刀
  4. [GetPortalCommentsPageByObjectIdResponse(id=1801523, encodeId=3b2d1801523a2, content=<a href='/topic/show?id=a88be40248f' target=_blank style='color:#2F92EE;'>#社会隔绝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74024, encryptionId=a88be40248f, topicName=社会隔绝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f9279, createdName=slcumt, createdTime=Tue May 15 18:23:00 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256618, encodeId=4618125661846, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6a6043, createdName=guoyibin, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267654, encodeId=c35d126e65452, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616774, encodeId=20161616e7402, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269873, encodeId=3fc12698e37f, content=学习了.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Dec 16 15:25:37 CST 2017, time=2017-12-16, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1801523, encodeId=3b2d1801523a2, content=<a href='/topic/show?id=a88be40248f' target=_blank style='color:#2F92EE;'>#社会隔绝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74024, encryptionId=a88be40248f, topicName=社会隔绝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f9279, createdName=slcumt, createdTime=Tue May 15 18:23:00 CST 2018, time=2018-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256618, encodeId=4618125661846, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6a6043, createdName=guoyibin, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267654, encodeId=c35d126e65452, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1616774, encodeId=20161616e7402, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Mon Dec 18 01:23:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269873, encodeId=3fc12698e37f, content=学习了.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Dec 16 15:25:37 CST 2017, time=2017-12-16, status=1, ipAttribution=)]
    2017-12-16 明天会更好!

    学习了.学习了.

    0

相关资讯

JAMA Psychiatry:新的研究发现,许多不同类型的焦虑和抑郁存在,你属于哪一种?

研究人员在斯坦福大学的一项研究中发现了五类新的精神疾病,这些类别涵盖了目前更广泛的焦虑和抑郁症的诊断。

EPJ Data Science:社交媒体照片显示抑郁症的预测标记

新研究发现,可以从抑郁症患者的社交媒体照片中识别出疾病,识别率高达70%。抑郁的人倾向于张贴较暗的照片,他们也更有可能使用滤镜将图像转换为黑白图像。

Clin Psycho Sci:大量的电子设备使用与抑郁症和自杀相关

发表在2017 Clinical Psychological Science杂志上的新研究发现,屏幕前的更多时间可能是青年人抑郁和自杀行为增加的原因。

J Affect Disord:别当和尚了,当心抑郁

新的研究表明,男性素食主义者患抑郁症的风险要高于正常吃肉的人。

Int J Geriatr Psychiatry:超过6年的抑郁和焦虑与视觉、听力和双重感官丧失之间的关系研究

最近,有研究人员在老年人中探究了双重和单独(视觉和听力)感官丧失与抑郁和焦虑症状之间的关系。研究包括了2890名年龄不小于60岁的老年人。主观视觉丧失、自我报道的听力损失或者双重感官丧失对抑郁和焦虑的影响通过贺普金斯症状检核表10来进行评估,并在时间基点和6年跟踪调查中利用了线性混合模型进行了分析。研究发现,听力损失与增加的抑郁(b = 0.1750, SE = 0.07, P = .02)和焦虑

Transl Psychi:别让足球成为抑郁的帮凶

对于球迷来说,或许几十年如一日的等待成就的不仅是工匠精神,还有可能是抑郁症,毕竟能从不断的失败中走出来并非易事。但对于当事者而言,他们可能承受的压力更大。