Sci Rep:自我报道的过敏性鼻炎中敏感模式和过敏原最小筛选组合

2017-09-07 AlexYang MedSci原创

皮刺试验(SPT)组合的优化,尤其是不同地区具有不同敏感性模式显著差异时,在中国显得很有必要。最近,有研究人员进行了旨在评估过敏性鼻炎(AR)中过敏原敏感性的模式和临床相关性,并且确定了SPT过敏原最小组合,并通过K?ppen-Geiger气候地图进行分类。研究总共包含了7148名自我报道AR的受试者,他们完成了一份标准的调查问卷,并且通过SPT来进行相关过敏原敏感性评估。研究发现,6340(88

皮刺试验(SPT)组合的优化,尤其是不同地区具有不同敏感性模式显著差异时,在中国显得很有必要。最近,有研究人员进行了旨在评估过敏性鼻炎(AR)中过敏原敏感性的模式和临床相关性,并且确定了SPT过敏原最小组合,并通过K?ppen-Geiger气候地图进行分类。

研究总共包含了7148名自我报道AR的受试者,他们完成了一份标准的调查问卷,并且通过SPT来进行相关过敏原敏感性评估。研究发现,6340(88.7%)的病人至少有一个阳性皮肤点刺反应,并且通过年龄、性别和地理区域分层,表现出了特异的敏感性模式。对屋尘螨(HDM)敏感性最高出现在中国南部,然而在中国西北部,3个最流行的过敏原为艾草、豚草和蒲公英花粉。 另外,更高的敏感比例和多重敏感性与AR并存病相关。8中过敏原(粉尘螨、 艾草、小蠊属、 榛子、 藜属植物、 点青霉、 动物皮屑和屋尘螨)在中国中部受试者敏感性测试中具有大于96%的鉴定率。另外,研究人员在不同地区长观察到了最优组合的差异,其中有5到6中过敏原对中国东北部、西北部和南部是均有很高效率的。最后,研究人员指出,这些SPT组合也许为中国筛选敏感性病人提供了廉价的工具。

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    2017-09-15 lofter

    我学习了.感谢分享

    0

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    2017-09-07 王秀

    学习了.涨知识了!

    0

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