BMJ:心电图或心脏磁共振成像确诊的未经辨识的心肌梗死患者预后

2020-05-08 MedSci原创 MedSci原创

研究认为,通过心电图或心脏磁共振成像确诊的未经辨识的心肌梗死患者预后相当,与急性心肌梗死患者不良预后风险相当,筛查未被识别的心肌梗死可能有助于心血管疾病高风险患者的风险分层

未经辨识的心肌梗死(unrecognised myocardial infarction)是一种特殊的病理现象,其缺少心肌梗死急性期特征,但可通过仪器手段监测到病理变化,近日研究人员比较了经心电图(UMI-ECG)或心脏磁共振成像(UMI-CMR)确认的未经辨识的心肌梗死患者预后差异。
 
研究收集了PubMed、Embase和Google Scholar数据。研究的主要结果是UMI-ECG和UMI-CMR确诊患者相关的主要心脏不良事件、全因死亡率和心血管死亡率。次要结果是复发性冠心病、心肌梗死、中风、心力衰竭和房颤风险。
 
荟萃分析包括30项研究,253425名参与者和1621920人-年随访。与无心肌梗死相比,UMI-ECG确诊患者的全因死亡率(危险比1.50)、心血管死亡率(2.33)和主要不良心脏事件(1.61)的风险增加,UMI-CMR确诊患者的全因死亡率(3.21)、心血管死亡率(10.79)和主要不良心脏事件(3.23)风险更高。与无心肌梗死患者相比,UMI-ECG确诊人群的全因死亡率的绝对危险为每1000人-年7.50例,心血管死亡绝对危险为11.04,主要不良心脏事件的绝对危险为27.45。UMI-CMR的相应数据分别为32.49、37.2和51.96。
 
研究认为,通过心电图或心脏磁共振成像确诊的未经辨识的心肌梗死患者预后相当,与急性心肌梗死患者不良预后风险相当,筛查未被识别的心肌梗死可能有助于心血管疾病高风险患者的风险分层。
 
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    2021-03-04 gaoxiaoe
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