期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Like any inherited protein deficiency disease, cystic fibrosis (CF) is a good candidate for gene replacement therapy. Despite the tremendous efforts o......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Wet age-related macular degeneration (wAMD) is characterized by the presence of choroidal neovascularization (CNV). Although there are som......
期刊： CURRENT GENE THERAPY, 2022; 22 (3)
Although cross-correction was discovered more than 50 years ago, and held the promise of drastically improving disease management, still no cure exist......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Cancer-related anemia (CRA) negatively influences cancer patients' survival, disease progression, treatment efficacy, and quality of life ......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Lung cancer is cancer with the highest incidence in the world, and there is obvious heterogeneity within its tumor. The emergence of singl......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Heterogeneous nuclear ribonucleoproteins (hnRNPs), a large family of RNA-binding proteins, have been implicated in tumor progression in mu......
期刊： CURRENT GENE THERAPY, 2022; 22 (2)
The increasing resistance of the disease-causing pathogens to antimicrobial drugs is a public health concern and a socio-economic burden. The emergenc......
期刊： CURRENT GENE THERAPY, 2022; 22 (3)
Peripheral artery diseases remain a serious public health problem. Although there are many traditional methods for their treatment using conservative ......
期刊： CURRENT GENE THERAPY, 2022; 22 (1)
Lung adenocarcinoma (LUAD) is the common histological subtype of non-small-cell lung carcinoma (NSCLC). Circular RNAs (circRNAs) represent a new class......
期刊： CURRENT GENE THERAPY, 2022; 22 (1)
Background: Radiation-induced lung injury (RILI) is lacking effective therapeutic strategies. In this study, we conducted TGF-beta 1-based CRISPR/Cas9......
期刊： CURRENT GENE THERAPY, 2022; 22 (2)
Background: Increasing research reveals that long non-coding RNAs (lncRNAs) play an important role in various biological processes of human diseases. ......
期刊： CURRENT GENE THERAPY, 2022; 22 (4)
Background: Exosomes released from cardiomyocytes (CMs) potentially play an important role in angiogenesis through microRNA (miR) delivery. Studies ha......
期刊： CURRENT GENE THERAPY, 2022; 22 (4)
Background: Female fertility refers to the capacity to produce oocytes and achieve fertilization and pregnancy, and it is impaired by age, disease, en......
期刊： CURRENT GENE THERAPY, 2022; 22 (5)
Background: Signal transducer and activator of transcription 3 (STAT3) is an oncogene and frequently overexpressed in cancers. However, the regulatory......
期刊： CURRENT GENE THERAPY, 2022; 22 (2)
Background: Scaffold-based gene therapy provides a promising approach for tissue engineering, which was important and popular as it combined medical a......
