期刊： JOURNAL OF BIOCHEMISTRY, 2023; 175 (1)
T7 phage libraries displaying random peptides are powerful tools for screening peptide sequences that bind to various target molecules. The T7 phage s......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; ()
The cytosolic peptide:N-glycanase (PNGase; NGLY1 in human and PNG1 in budding yeast) is a deglycosylating enzyme widely conserved in eukaryotes. Initi......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 174 (2)
Here, we show that 3,5-bis[(1E)-2-(2,6-dichlorophenyl)ethenyl]-1H-pyrazole 2l depolymerizes microtubules and reduces the number of growing tips of mic......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 174 (6)
The cGAS-STING innate immune pathway has recently emerged as a critical driver of inflammation in a variety of settings, such as virus infection, cell......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 174 (6)
Sterile alpha and Toll/interleukin receptor motif-containing protein 1 (SARM1) is a NAD(+) hydrolase that plays a key role in axonal degeneration and ......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 173 (3)
VHH antibodies or nanobodies, which are antigen-binding domains of heavy chain antibodies from camelid species, have several advantageous characterist......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 174 (1)
RAD52 is a single-stranded DNA (ssDNA) binding protein that functions in the repair of DNA double-strand breaks (DSBs) by promoting the annealing of c......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 174 (1)
Nicotinamide-N-methyltransferase (NNMT) is an enzyme that consumes S-adenosyl-methionine (SAM) and nicotinamide (NAM) to produce S-adenosyl-homocystei......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; ()
Many lysosomal enzymes contain N-glycans carrying mannose 6-phosphate (M6P) residues. Modifying lysosomal enzymes by M6P residues requires a two-step ......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 173 (3)
Microglia are immune cells in the central nervous system that engulf unnecessary synapses during development. In vivo imaging has substantially improv......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; ()
Proteins that exsert physiological functions during being translated have been discovered from prokaryotes to eukaryotes. These proteins, also called ......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 174 (1)
The lipopolysaccharide (LPS)-triggered horseshoe crab coagulation cascade is composed of three protease zymogens, prochelicerase C (proC), prochelicer......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; ()
Protein methylation is mainly observed in lysine, arginine and histidine residues. Histidine methylation occurs at one of two different nitrogen atoms......
期刊： JOURNAL OF BIOCHEMISTRY, 2023; 174 (4)
To identify amino acids that play important roles in the structural stability of Fab, seven phenylalanine residues in the Fab constant region of the t......
