Novel synthetic biological study on intracellular distribution of human GlcNAc-1-phosphotransferase expressed in insect cells

Kiriyama, K; Fujioka, K; Kawai, K; Mizuno, T; Shinohara, Y; Itoh, K

Itoh, K (通讯作者),Jichi Med Univ, Sch Med, Dept Pediat, 3311-1,Yakushiji, Shimotsuke, Tochigi 3290498, Japan.;Itoh, K (通讯作者),Tokushima Univ, Inst Adv Med Sci, Dept Med Biotechnol, 3,Kuramotocho, Tokushima, Tokushima 7708503, Japan.

JOURNAL OF BIOCHEMISTRY, 2023; ():

Abstract

Many lysosomal enzymes contain N-glycans carrying mannose 6-phosphate (M6P) residues. Modifying lysosomal enzymes by M6P residues requires a two-step ......

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