期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (1)
Metastases account for the majority of mortalities related to breast cancer. The onset and sustained presence of hypoxia strongly correlates with incr......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (2)
Loss-of-function somatic mutations of STK11, a tumor suppressor gene encoding LKB1 that contributes to the altered metabolic phenotype of cancer cells......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (11)
Dysregulation of Sonic hedgehog (SHH) signaling drives the growth of distinct cancer subtypes, including medulloblastoma (MB). Such cancers have been ......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (2)
Over 80% of women with high-grade serous ovarian cancer (HGSOC) develop tumor resistance to chemotherapy and die of their disease. There are currently......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (9)
Physiologic roles of copper in metabolic homeostasis have been well established; however, whether and how copper is dysregulated in tumors and contrib......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (9)
? Cancer cells feature increased macromolecular biosynthesis to support the formation of new organelles and membranes for cell division. In particular......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (11)
The mechanisms of how cancer cells are selected and evolve to establish distant metastatic colonies remain unclear. Tumor het-erogeneity and lack of b......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (11)
Acute myeloid leukemia (AML) is a hematologic malignancy metabolically dependent on oxidative phosphorylation and mito-chondrial electron transport ch......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (1)
Stromal cells play a central role in promoting the progression of colorectal cancer. Here, we analyze molecular changes within the epithelial and stro......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (4)
To better understand the signaling complexity of AXL, a member of the tumor- associated macrophage (TAM) receptor tyrosine kinase family, we created a......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (5)
A common outcome of androgen deprivation in prostate cancer therapy is disease relapse and progression to castration-resistant prostate cancer (CRPC) ......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (6)
Inhibiting androgen signaling using androgen signaling inhibitors (ASI) remains the primary treatment for castrate-resistant prostate cancer. Acquired......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (7)
In comparison with intestinal-type gastric cancer, diffuse-type gastric cancer (DGC) is more likely to recur, metastasize, and exhibit worse clinical ......
期刊： MOLECULAR CANCER RESEARCH, 2022; 20 (3)
AXL, a receptor tyrosine kinase from the TAM (TYRO3 AXL and MER) subfamily, and its ligand growth arrest-specific 6 (GAS6) are implicated in pathogene......
