A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog-Dependent Tumor Growth

Yang, F; Rodriguez-Blanco, J; Long, J; Swiderska-Syn, M; Wynn, DT; Li, B; Shen, C; Nayak, A; Ban, YG; Sun, XD; Suter, RK; McCrea, HJ; Capobianco, AJ; Ayad, NG; Robbins, DJ

Robbins, DJ (通讯作者),Georgetown Univ, Lombardi Comprehens Canc Ctr, Dept Oncol, New Res Bldg,3970 Reservoir Rd NW, Washington, DC 20057 USA.

MOLECULAR CANCER RESEARCH, 2022; 20 (11): 1598

Abstract

Dysregulation of Sonic hedgehog (SHH) signaling drives the growth of distinct cancer subtypes, including medulloblastoma (MB). Such cancers have been ......

Full Text Link