GAS6/AXL Inhibition Enhances Ovarian Cancer Sensitivity to Chemotherapy and PARP Inhibition for through Increased DNA Damage and Enhanced Replication Stress

Mullen, MM; Lomonosova, E; Toboni, MD; Oplt, A; Cybulla, E; Blachut, B; Zhao, PN; Noia, H; Wilke, D; Rankin, EB; Kuroki, LM; Hagemann, AR; Hagemann, IS; McCourt, CK; Thaker, PH; Mutch, DG; Powell, MA; Mosammaparast, N; Vindigni, A; Fuh, KC

Fuh, KC (通讯作者)，Washington Univ, Alvin J Siteman Canc Ctr, Dept Obstet & Gynecol, Div Gynecol Oncol,Sch Med, 425 South Euclid Ave,CB 8064, St Louis, MO 63110 USA.

MOLECULAR CANCER RESEARCH, 2022; 20 (2): 265

Abstract

Over 80% of women with high-grade serous ovarian cancer (HGSOC) develop tumor resistance to chemotherapy and die of their disease. There are currently......

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