UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridine moieties

Jang, S; Raja, SJ; Roginskaya, V; Schaich, MA; Watkins, SC; Van Houten, B

Van Houten, B (通讯作者),Univ Pittsburgh, UPMC Hillman Canc Ctr, Pittsburgh, PA 15213 USA.;Van Houten, B (通讯作者),Univ Pittsburgh, Sch Med, Mol Pharmacol Grad Program, Pittsburgh, PA 15213 USA.;Van Houten, B (通讯作者),Univ Pittsburgh, Sch Med, Dept Pharmacol & Chem Biol, Pittsburgh, PA 15213 USA.

NUCLEIC ACIDS RESEARCH, 2023; 51 (10): 4881

Abstract

UV-damaged DNA-binding protein (UV-DDB) is a heterodimeric protein, consisting of DDB1 and DDB2 subunits, that works to recognize DNA lesions induced ......

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