CRISPR-Cas12a trans-cleaves DNA G-quadruplexes

Li, Y; Li, T; Liu, BF; Hu, R; Zhu, J; He, T; Zhou, X; Li, CG; Yang, YH; Liu, ML

CHEMICAL COMMUNICATIONS, 2020; 56 (83): 12526

Abstract

We for the first time report that the activated CRISPR-Cas12a system trans-cleaves DNA G-quadruplexes (G4). The cleavage activity on human telomere G4......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索