Part III: Novel checkpoint kinase 2 (Chk2) inhibitors; design, synthesis and biological evaluation of pyrimidine-benzimidazole conjugates

Galal, SA; Khattab, M; Shouman, SA; Ramadan, R; Kandil, OM; Kandil, OM; Tabll, A; El Abd, YS; El-Shenawy, R; Attia, YM; El-Rashedy, AA; El Diwani, HI

Galal, SA (reprint author), Natl Res Ctr, Div Pharmaceut & Drug Ind, Dept Chem Nat & Microbial Prod, Cairo 12622, Egypt.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018; 146 (): 687

Abstract

Recently a dramatic development of the cancer drug discovery has been shown in the field of targeted cancer therapy. Checkpoint kinase 2 (Chk2) inhibi......

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