SMAD4 impedes the conversion of NK cells into ILC1-like cells by curtailing non-canonical TGF-beta signaling

Cortez, VS; Ulland, TK; Cervantes-Barragan, L; Bando, JK; Robinette, ML; Wang, QL; White, AJ; Gilfillan, S; Cella, M; Colonna, M

Colonna, M (reprint author), Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA.

NATURE IMMUNOLOGY, 2017; 18 (9): 995

Abstract

Among the features that distinguish type 1 innate lymphoid cells (ILC1s) from natural killer (NK) cells is a gene signature indicative of 'imprinting'......

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