PLoS One:颈动脉狭窄患者发生开角型青光眼的风险研究

2018-05-09 cuiguizhong MedSci原创

台湾台中军区总医院眼科的Chou CC近日在PLoS One发表了一项工作,他们研究了颈动脉狭窄(CAS)是否是开角型青光眼的危险因素。在这项研究中,他们调查了台湾国民健康保险(NHI)计划索赔数据,对台湾人群中CAS与开角型青光眼发展之间的关系进行了研究。

台湾台中军区总医院眼科的Chou CC近日在PLoS One发表了一项工作,他们研究了颈动脉狭窄(CAS)是否是开角型青光眼的危险因素。在这项研究中,他们调查了台湾国民健康保险(NHI)计划索赔数据,对台湾人群中CAS与开角型青光眼发展之间的关系进行了研究。

本研究将1999至2010年间2093例CAS患者和8372例无CAS的、年龄和性别匹配的患者纳入研究范围。他们随访到2013年12月31日,在随访期间,他们对开角型青光眼(OAG)患者进行确诊。与对照组相比,采用相关比例风险模型来评估CAS对OAG的风险比(HR)。

他们发现,患CAS人群中开角型青光眼的HR为1.50(95%置信区间,1.11-2.02,P = 0.008)。 Kaplan-Meier分析显示,颈动脉狭窄(CAS)对 OAG的累积发生率高于对照组(log-rank test,P <0.001)。

因此,他们认为,颈动脉狭窄(CAS)是开角型青光眼(OAG)发展的显着的独立危险因素。他们的发现对于人口老龄化具有临床意义,因为CAS越来越普遍。

原文出处:

Chou, C.C., et al., Risk of developing open-angle glaucoma in patients with carotid artery stenosis: A nationwide cohort study. PLoS One, 2018. 13(4): p. e0194533.

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    2018-08-14 wmw990556

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    2018-05-16 半夏微凉

    学习了谢谢分享

    0

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