手术麻醉典型病例:肝母细胞瘤手术

2017-05-02 张建敏 《小儿手术麻醉典型病例精选》

一般情况患儿,男,1岁2个月,体重13kg。患儿于入院前3个月因食欲缺乏至当地医院就诊,结合临床症状、体格检查和相关检查结果(B超和CT),考虑为肝脏肿瘤。我院门诊B超提示肝母细胞瘤,大小约为12.1cm×9.3cm×13.6cm,甲胎蛋白(α-fetoprotein,AFP)结果为1 422 100ng/ml,临床诊断为肝母细胞瘤。予长春新碱1mg 1天,氟尿嘧啶15mg 5天,顺铂10mg 5


一般情况

患儿,男,1岁2个月,体重13kg。患儿于入院前3个月因食欲缺乏至当地医院就诊,结合临床症状、体格检查和相关检查结果(B超和CT),考虑为肝脏肿瘤。我院门诊B超提示肝母细胞瘤,大小约为12.1cm×9.3cm×13.6cm,甲胎蛋白(α-fetoprotein,AFP)结果为1 422 100ng/ml,临床诊断为肝母细胞瘤。予长春新碱1mg 1天,氟尿嘧啶15mg 5天,顺铂10mg 5天化疗,待4个疗程后进行评价,B超及CT结果均提示瘤体缩小,大小约为5.1cm× 5.3cm×5.8cm,AFP结果为68.65ng/ml。为行手术治疗收入院。入院体格检查:神志清,一般状态可,口唇、面色无苍白,皮肤弹性好,皮下脂肪饱满。腹外形膨隆,未及明确肿物,全腹无压痛、反跳痛及肌紧张,肝脾肋下未及,叩诊鼓音,移动性浊音阴性,肠鸣音3 次/分。血生化:总蛋白(TP)52.9g/L,谷草转氨酶(AST)640.0U/L,谷丙转氨酶(ALT)451.0U/L,CK 556.0U/L,乳酸脱氢酶(LDH)434.0U/L。余化验检查大致正常。予常规术前检查,除外手术禁忌,备血,做好术前准备,于入院后第二天行手术。

麻醉过程

术前于病房行胃肠减压,入室常规监护后行麻醉诱导,静脉给予阿托品0.1mg,甲强龙10mg,芬太尼25μg,丙泊酚40mg,罗库溴铵10mg,待睫毛反射消失,托下颌无体动时,置入带囊4.0mm(ID)气管导管,插管深度12cm,听诊双肺呼吸音对称后固定气管导管,氧流量设为2L/min。机械通气设置VT 120ml,RR 22次/分,控制PETCO2在35~45mmHg范围内,I∶E= 1∶1.5。另予静脉泵入丙泊酚8mg/(kg/h)及瑞芬太尼0.3μg/(kg?min),维持麻醉深度。后行桡动脉穿刺置管测压,术中持续监测BP变化,指导麻醉深度控制及输血输液。开放颈外静脉通路,以备术中快速大量输液需要。手术时间共6小时,麻醉时间7小时,出血10ml,术中补充病房带入液20ml,复方乳酸山梨醇溶液700ml,羟乙基淀粉溶液150m l。共进行动脉血气检查(arterial blood gases,ABGs)2次,Hb术毕时测大于8g/L,故未给予输血治疗,使用5% NaHCO3溶液25ml,纠正酸中毒。术毕前15分钟停止丙泊酚泵入,降低瑞芬太尼输注速度为0.1μg/(kg?h)于皮内缝合结束后停止。约5分钟后患儿自主呼吸恢复,吸痰时存在呛咳反射,待VT达到100ml,RR到达25次/分时,脱氧3分钟,观察SpO2可维持在98%。后充分吸氧、吸除气管及口腔内分泌物,拔除气管导管。患儿睁眼,有自主体动,哭声有力,SpO2维持好,送入PACU。患儿在恢复室中停留大约30分钟,神志清,言语清晰,镇静评分合格,安返病房。术后第二天访视患儿,一般情况可,体温最高37.3℃,生命体征平稳,无头痛、恶心、呕吐,无腹痛腹胀,已排气、排便。术后对症支持治疗,患儿恢复良好,第7天出院。

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    2019-06-25 1861d29b3em

    请问这是哪个医院的案例?

    0

  2. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed May 03 08:24:10 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193144, encodeId=f32d19314446, content=学习并分享!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed May 03 06:59:25 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193124, encodeId=e57a19312429, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Wed May 03 06:41:24 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-04 大爰

    实用的知识学习了!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=368331, encodeId=99d1368331fd, content=请问这是哪个医院的案例?, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kw7OiaxskvRMiama0PFxgLo3GWeYOc7ZbrgMMKDbLXQPbRr2NRMBTU4TrTpNzUFO463kL1kMzc8bFl/0, createdBy=225c1936033, createdName=1861d29b3em, createdTime=Tue Jun 25 14:25:46 CST 2019, time=2019-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1772225, encodeId=87561e7222585, content=<a href='/topic/show?id=c38963544cc' target=_blank style='color:#2F92EE;'>#母细胞瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63544, encryptionId=c38963544cc, topicName=母细胞瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, 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likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Thu May 04 07:45:15 CST 2017, time=2017-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193462, encodeId=57141934627d, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Thu May 04 02:15:33 CST 2017, time=2017-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193178, encodeId=3bf01931e84c, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed May 03 08:24:10 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193144, encodeId=f32d19314446, content=学习并分享!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed May 03 06:59:25 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193124, encodeId=e57a19312429, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Wed May 03 06:41:24 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-04 飛歌

    学习了很有用

    0

  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed May 03 08:24:10 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193144, encodeId=f32d19314446, content=学习并分享!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed May 03 06:59:25 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193124, encodeId=e57a19312429, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Wed May 03 06:41:24 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-03 飛歌

    学习了很有用

    0

  9. 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likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Thu May 04 07:45:15 CST 2017, time=2017-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193462, encodeId=57141934627d, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Thu May 04 02:15:33 CST 2017, time=2017-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193178, encodeId=3bf01931e84c, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed May 03 08:24:10 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193144, encodeId=f32d19314446, content=学习并分享!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed May 03 06:59:25 CST 2017, time=2017-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193124, encodeId=e57a19312429, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/udqvoAsWtvRVficPKOpMh4M31O9bJ8jMiaUHAheeNpIqMapC8mUnBWfEskrcVjofbicWU4icRD6vFvVeEYlPmSbXELickazEGVFYO/0, createdBy=24741603767, createdName=医艺依意, createdTime=Wed May 03 06:41:24 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-03 大爰

    学习并分享!!!

    0

  10. 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    2017-05-03 医艺依意

    学习了,谢谢分享

    0

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