DCR:结肠镜检查开始时间与腺瘤检出率的关系

2020-08-13 MedSci原创 MedSci原创

隐藏在人体肠道内的癌症正侵蚀着人们的健康,统计显示,全球每年新发病例约800万人,结肠癌更在中国恶性肿瘤排行榜上步入“三甲”。据我国结肠癌患者数据统计,结肠癌呈现年轻化特点,最小的患者只有24岁。

        隐藏在人体肠道内的癌症正侵蚀着人们的健康,统计显示,全球每年新发病例约800万人,结肠癌更在中国恶性肿瘤排行榜上步入“三甲”。据我国结肠癌患者数据统计,结肠癌呈现年轻化特点,最小的患者只有24岁。

        肠镜是诊断肠道疾病最准确、可靠的方法。但目前,不管个人体检还是单位体检,出于对检查痛苦的恐惧,肠镜成为体检最大的“黑洞”。最近有研究认为什么时候做肠镜也与我们检查肠镜结果有很大的关系,特别是结肠腺瘤的检出率与肠镜时间段有很大的关系。

        我们知道肠道准备情况,病人是否采用全麻等因素会影响内镜医师的操作从而影响肠镜检查结果的判断。那么上午做肠镜还是下午做肠镜对于结肠镜检查结果是否有影响呢?本项研究对此进行了相应的探究。

                                              DOI:https://doi.org/10.1016/j.dld.2020.06.011

        研究人员对2011年1月1日至2015年6月30日间在哥伦比亚大学欧文医学中心行肠镜常规筛查的大于50岁以上的患者进行了回顾性研究。研究人员将患者分为三组:按时完成肠镜检查组;推迟肠镜检查1-2小时组以及推迟肠镜检查大于2小时组。主要观察结果是结肠腺瘤的检出率(ADR)和停用麻药时间。多变量logistic回归用于确定肠镜开始时间延迟对ADR的影响,多变量线性回归用于评估肠镜开始时间延迟与撤减麻药时间之间的关联。

        本项研究共纳入了7905例进行结肠镜检查的患者,包括5390例早晨病例和2515例下午病例。患者平均年龄为61岁,女性为57.5%。其中5402例早/早开始或延迟≤1 h的病例,2043例延迟1-2 h的病例和460例延迟> 2 h的病例。所有患者的总ADR率为25.25%。上午和下午病例的ADR差异均无统计学意义(分别为25.16%和25.45%,p值= 0.783)。在多变量分析中,与延迟≤1h的病例相比,延迟1-2 h的病例与腺瘤检出率显着下降相关(OR 0.88,95%CI 0.78-1.00,p  = 0.049)。

 

        因此,本项研究最后学者说道:肠镜检查应该准时准点开展,推迟肠镜开始超过1小时会导致腺瘤检出率降低。

 

原始出处:

Monika Laszkowska. Et al. Delays in colonoscopy start time are associated with reductions in adenoma detection rates. Dig Liver Dis.2020.

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    2022-03-05 ms8000000118728776

    学习了

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    2020-11-03 474576351

    积分呀

    0

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    2020-08-15 zhouqu_8
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    2020-08-13 Jessica

    推迟肠镜检查1-2小时是什么意思呢?#肠镜检查#

    0

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    2020-08-13 12543f43m99暂无昵称

    学习

    0

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