Nature:评估非药物干预对欧洲COVID-19的影响

2020-06-09 MedSci原创 MedSci原创

主要的非药物干预措施,特别是封锁措施对减少传播有很大的作用。应考虑继续采取干预措施,使SARS-CoV-2的传播得到控制。

新型冠状病毒(SARS-CoV-2)出现并在中国境外传播后,欧洲出现了大规模的疫情。对此,欧洲许多国家实施了前所未有的非药物干预措施,如关闭学校、全国封锁等。

最近,研究人员探究了从COVID-19开始到2020年5月4日(封锁解除),欧洲11个国家采取的主要干预措施的影响。

该模型从观察到的死亡病例向后计算,以估计几周前发生的传播,允许感染和死亡之间的时间滞后。研究人员使用了国家间的部分信息汇总,对繁殖数量有单独和共同的影响。汇集使得更多的信息得以被用,有助于克服数据的特异性,并使估计更加及时。

研究人员的模型依赖于一些流行病学参数的固定估计,如感染死亡率,不包括输入或次国家差异,并假设繁殖数量的变化是对干预措施的即时反应,而不是行为的逐渐变化。

在持续的大流行中,研究人员此时所依赖的死亡数据是不完整的,报告中存在系统性的偏差,并且有待未来的整合。

研究人员估计,对于考虑中的所有国家,目前的干预措施已经足以将繁殖数𝑅𝑡控制地低于1(概率𝑅𝑡<1.0为99.9%),实现疫情控制。研究人员估计,截至5月4日,在所有11个国家中,有1200万至1500万人感染了SARS-CoV-2,占人口的3.2%至4.0%。

该结果表明,主要的非药物干预措施,特别是封锁措施对减少传播有很大的作用。应考虑继续采取干预措施,使SARS-CoV-2的传播得到控制。

 

原始出处:

Seth Flaxman et al. Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe, Nature (2020). 

 

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1640765, encodeId=332c1640e6525, content=<a href='/topic/show?id=73b88e73171' target=_blank style='color:#2F92EE;'>#药物干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87731, encryptionId=73b88e73171, topicName=药物干预)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sun Apr 11 12:56:29 CST 2021, time=2021-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884371, encodeId=d07018843e14e, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Jun 14 15:56:29 CST 2020, time=2020-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813795, encodeId=5ed5813e9593, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:19:33 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339328, encodeId=51cf13393289c, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Thu Jun 11 08:56:29 CST 2020, time=2020-06-11, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1640765, encodeId=332c1640e6525, content=<a href='/topic/show?id=73b88e73171' target=_blank style='color:#2F92EE;'>#药物干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87731, encryptionId=73b88e73171, topicName=药物干预)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sun Apr 11 12:56:29 CST 2021, time=2021-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884371, encodeId=d07018843e14e, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Jun 14 15:56:29 CST 2020, time=2020-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813795, encodeId=5ed5813e9593, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:19:33 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339328, encodeId=51cf13393289c, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Thu Jun 11 08:56:29 CST 2020, time=2020-06-11, status=1, ipAttribution=)]
    2020-06-14 liye789132251
  3. [GetPortalCommentsPageByObjectIdResponse(id=1640765, encodeId=332c1640e6525, content=<a href='/topic/show?id=73b88e73171' target=_blank style='color:#2F92EE;'>#药物干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87731, encryptionId=73b88e73171, topicName=药物干预)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sun Apr 11 12:56:29 CST 2021, time=2021-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884371, encodeId=d07018843e14e, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Jun 14 15:56:29 CST 2020, time=2020-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813795, encodeId=5ed5813e9593, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:19:33 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339328, encodeId=51cf13393289c, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Thu Jun 11 08:56:29 CST 2020, time=2020-06-11, status=1, ipAttribution=)]
    2020-08-27 14818eb4m67暂无昵称

    学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1640765, encodeId=332c1640e6525, content=<a href='/topic/show?id=73b88e73171' target=_blank style='color:#2F92EE;'>#药物干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87731, encryptionId=73b88e73171, topicName=药物干预)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sun Apr 11 12:56:29 CST 2021, time=2021-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884371, encodeId=d07018843e14e, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Sun Jun 14 15:56:29 CST 2020, time=2020-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813795, encodeId=5ed5813e9593, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:19:33 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339328, encodeId=51cf13393289c, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Thu Jun 11 08:56:29 CST 2020, time=2020-06-11, status=1, ipAttribution=)]

相关资讯

JAMA:河南家族性聚集性病例:2人严重肺炎,3人中度感染

2月21日,河南省人民医院医学影像科王梅云等在JAMA在线发表一个家族性病例报告,该家族中1名无任何症状、CT也完全正常、仅核酸检测阳性且有武汉居住史的年轻女士,传染了5人。

MedRxiv: 8℃适合病毒传播!?

近日,中山大学公共卫生学院学者在医学预印本平台MedRxiv刊登研究,针对27个国家429个城市约2.5万例确诊新冠肺炎患者,通过统计各地确诊人数和对应节点的气温,发现当气温在8℃左右时,新冠肺炎可能最适合传播。

MedRxiv: 新冠病毒可通过眼结膜传播?武大人民医院全新临床研究:无证据

近日,发表在预印本网站medRxiv(未经同行评议)的一篇论文中,来自武汉大学人民医院陈长征团队的回顾性队列研究表明,新型冠状病毒(SARS-CoV-2)经结膜传播的途径没有得数据支持。

CELL:美国早期SARS-CoV-2流行期间的传播情况

通过耦合该基因组数据与国内和国际旅行模式,研究人员表明,早期SARS-CoV-2在康涅涅狄格州的传播很可能是由国内引进所驱动的。

NEJM:尼帕病毒传播

由此可见,年龄增长和呼吸道症状是尼帕病毒传染性的指标。控制人与人之间传播的干预措施应旨在减少体液接触。

NEJM:发表新型肺炎初期传播特点,如果及早公开信息,武汉大瘟疫将会怎样?

此前,国际顶级医学期刊《柳叶刀》(Lancet)发表了7篇关于新型冠状病毒的文章(包括4篇原创研究论文、2篇评论及1篇社论),而世界卫生组织也连发了8份新型冠状病毒疫情的报告,表现了对于该疫情极大的关注。