JACC:经导管主动脉瓣置换术后的再次手术

2020-07-23 xiangting MedSci原创

与一开始就接受SAVR的患者相比,TAVR早期失败后再进行SAVR虽然少见,但预后不良。

这项研究使用胸外科医师协会(STS)成人心脏手术数据库,报道了经导管主动脉瓣置换术(TAVR)后再次进行外科手术的最大患者系列。

TAVR已成为治疗主动脉瓣狭窄的有效手段。随着TAVR逐渐被用于低风险人群,装置失效的治疗变得越来越重要。

在STS成人心脏手术数据库中查找2011年至2015年接受外科主动脉瓣置换并有TAVR史的患者。确定实际/预期(O/E)死亡率比值,以方便对不同手术指征和TAVR手术后时间进行比较。

共有123名患者符合入选标准(中位年龄77岁),分别有17%、24%和59%的患者STS预测死亡风险为 4%、4%-8%和>8%。再次手术的中位时间为2.5个月(四分位范围:0.7-13.0),手术死亡率为17.1%。再次手术的常见指征包括早期TAVR装置失效,如瓣周漏(15%)、结构性瓣膜退化(11%)、修复失败(11%)、尺寸或位置问题(11%)和瓣膜性心内膜炎(10%)。所有的术前风险类别均与O/E死亡率比值升高相关(预测死亡风险<4%:O/E 5.5;4%-8%:O/E 1.7;>8%:O/E 1.2) 。

与一开始就接受SAVR的患者相比,TAVR早期失败后再进行SAVR虽然少见,但预后不良。对于这种不断发展的技术,需要继续积累经验以减少早期TAVR失败的发生率,并进一步确定TAVR瓣膜失效的最佳治疗方法。

原始出处:

Oliver K. Jawitz. Reoperation After Transcatheter Aortic Valve Replacement An Analysis of the Society of Thoracic Surgeons Database. JACC:Cardiovascular Interventions. July 2020.

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    2021-01-23 hbwxf
  2. 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    2020-12-15 14818eb4m67暂无昵称

    学习了

    0

  3. 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    2020-10-14 yxch48
  4. 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    2020-07-25 147b4f4dm25暂无昵称

    学习一下

    0

  5. 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  6. 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  7. 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  8. 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  9. 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    2020-07-25 lsj631
  10. 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