ASCO 2022:经历过胃癌手术的患者,代谢综合征和脂肪肝患病风险较低

2022-06-01 MedSci原创 MedSci原创

在消化道恶性肿瘤中,胃癌发病率位居前列,然而,胃癌患者的代谢综合征和脂肪肝发病风险尚不清楚。

近年来,随着医疗水平的高速发展,癌症治疗的不断深入和优化,癌症幸存者的数量正在迅速增加。在消化道恶性肿瘤中,胃癌发病率位居前列,然而,胃癌患者的代谢综合征和脂肪肝发病风险尚不清楚。

近日,研究人员调查了与非癌症受试者相比,胃癌幸存者中代谢综合征和脂肪肝的患病率和患病风险,还分析了代谢功能障碍相关脂肪肝 (MAFLD) 的发病风险。研究结果已在2022年ASCO大会上公布。

在这项横断面研究中,研究人员招募了2014年~2019年Gangnam Severance医院进行健康体检的参与者。在经过年龄和性别 1:4 倾向评分匹配后,共纳入119名胃癌幸存者和476名非癌症受试者,其中,胃癌幸存者分为胃癌手术幸存者(OpGC)(n = 95)和非手术幸存者(non-OpGC)(n = 24)。MetS是通过代谢成分诊断的,脂肪肝是通过超声检查评估的。

结果显示,21.0%的胃癌幸存者和30.5%的非癌症受试者出现了MetS,13.7%的OpGC幸存者和50.0%的非OpGC幸存者出现了MetS。25.2%的胃癌幸存者和37.6%的非癌症受试者,以及21.1%的OpGC幸存者和41.7%的非OpGC幸存者观察到脂肪肝。

在调整年龄和性别后,OpGC 幸存者的 MetS 风险显著降低。与非癌症受试者相比,OpGC 幸存者的脂肪肝风险显著降低,但在非 OpGC 幸存者中则不然。与非癌症受试者相比,OpGC 幸存者代谢功能障碍相关脂肪肝疾病的风险明显降低。

总之,与非癌症受试者相比,OpGC 幸存者的MetS脂肪肝患病风险较低。未来,可进一步探索这些关联,以确保对胃癌幸存者进行及时的医疗干预。

原始出处

Hyojin Park.Risk of metabolic syndrome and fatty liver in gastric cancer survivors: A propensity score-matched analysis.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1939382, encodeId=22481939382c8, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Aug 10 12:44:48 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281807, encodeId=0e4d128180e75, content=<a href='/topic/show?id=ef315299070' target=_blank style='color:#2F92EE;'>#患病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52990, encryptionId=ef315299070, topicName=患病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1432326, encodeId=16011432326d5, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1511931, encodeId=2bea1511931f7, content=<a href='/topic/show?id=8e2983235df' target=_blank style='color:#2F92EE;'>#胃癌手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83235, encryptionId=8e2983235df, topicName=胃癌手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=43ea10414088, createdName=12498568m53暂无昵称, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=)]
    2022-08-10 quxin068
  2. [GetPortalCommentsPageByObjectIdResponse(id=1939382, encodeId=22481939382c8, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Aug 10 12:44:48 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281807, encodeId=0e4d128180e75, content=<a href='/topic/show?id=ef315299070' target=_blank style='color:#2F92EE;'>#患病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52990, encryptionId=ef315299070, topicName=患病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1432326, encodeId=16011432326d5, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1511931, encodeId=2bea1511931f7, content=<a href='/topic/show?id=8e2983235df' target=_blank style='color:#2F92EE;'>#胃癌手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83235, encryptionId=8e2983235df, topicName=胃癌手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=43ea10414088, createdName=12498568m53暂无昵称, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1939382, encodeId=22481939382c8, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Aug 10 12:44:48 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281807, encodeId=0e4d128180e75, content=<a href='/topic/show?id=ef315299070' target=_blank style='color:#2F92EE;'>#患病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52990, encryptionId=ef315299070, topicName=患病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1432326, encodeId=16011432326d5, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1511931, encodeId=2bea1511931f7, content=<a href='/topic/show?id=8e2983235df' target=_blank style='color:#2F92EE;'>#胃癌手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83235, encryptionId=8e2983235df, topicName=胃癌手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=43ea10414088, createdName=12498568m53暂无昵称, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1939382, encodeId=22481939382c8, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Wed Aug 10 12:44:48 CST 2022, time=2022-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281807, encodeId=0e4d128180e75, content=<a href='/topic/show?id=ef315299070' target=_blank style='color:#2F92EE;'>#患病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52990, encryptionId=ef315299070, topicName=患病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1432326, encodeId=16011432326d5, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1511931, encodeId=2bea1511931f7, content=<a href='/topic/show?id=8e2983235df' target=_blank style='color:#2F92EE;'>#胃癌手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83235, encryptionId=8e2983235df, topicName=胃癌手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=43ea10414088, createdName=12498568m53暂无昵称, createdTime=Fri Jun 03 04:44:48 CST 2022, time=2022-06-03, status=1, ipAttribution=)]

相关资讯

爱大蒜的理由找到了!BMJ:22年国人研究显示,长年吃大蒜,胃癌死亡风险降低34%

BMJ:持续7年摄入大蒜补剂与胃癌死亡风险降低有关,与幽门螺杆菌治疗两周、摄入维生素补充剂7年有着相似的效果,但与胃癌发病率降低无关。

BMC Med:阿帕替尼+奥沙利铂+卡培他滨新辅助治疗局部晚期胃癌/胃食管交界处癌

采用阿帕替尼、奥沙利铂和卡培他滨联合方案作为局部晚期胃/胃食管交界处腺癌的新辅助治疗的前期可期

幽门螺杆菌研究获重大突破!这种美容因子竟是致癌帮凶

今年的5月29日是第18个“世界肠道健康日”,自2005年来世界胃肠病学组织(WGO)将每年的5月29日定为世界肠道健康日,旨在提醒人们注意肠道发出的警示,注意身体健康。

患者明明是颈胸背部疼痛,为何却戴上了一枚凶险的“戒指”?

贫血貌,全身皮肤黏膜无黄染,未见散在瘀点、瘀斑,周身浅表淋巴结未触及肿大,双肺叩诊呈浊音,两肺底呼吸音低,心律齐,心音有力,各瓣膜听诊区未闻及杂音。

胃癌常用免疫组化指标解读,看这一篇就够了!

“对症下药”才能“药到病除”。

J Gastroenterol:胃癌筛查计划对胃癌患者的长期预后的影响

采用上消化道内窥镜检查或在确诊前两年内进行胃癌筛查的患者的预后最好