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Sci Rep：心理压力与唾液及血液中的炎症因子的水平相关

2018-02-28 MedSci MedSci原创

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唾液收集被认为是一种非侵入性的方法，用来检测炎症标志物对自然社会背景下情绪状态的反应。许多研究认为细胞因子在调节社交和情绪行为的不同方面发挥重要作用。这项研究的目的是调查血浆和唾液作为测量一些炎症标志物水平（CRP，IL-1β，IL-18和IL-6）的研究材料的可靠性。同时，考虑了这些标记与情绪状态之间的关系对社会认知压力（Academic Exam，AE）的反应。结果已证明所有免疫介质分析的血浆

唾液收集被认为是一种非侵入性的方法，用来检测炎症标志物对自然社会背景下情绪状态的反应。许多研究认为细胞因子在调节社交和情绪行为的不同方面发挥重要作用。这项研究的目的是调查血浆和唾液作为测量一些炎症标志物水平（CRP，IL-1β，IL-18和IL-6）的研究材料的可靠性。同时，考虑了这些标记与情绪状态之间的关系对社会认知压力（Academic Exam，AE）的反应。

结果已证明所有免疫介质分析的血浆和唾液浓度在整个社会认知压力中明显相关。另外，当与AE密切相关时，愤怒状态，IL-1β，IL-18唾液和血浆浓度显著更高，而在AE期间它们减少。另一方面，在整个AE期间焦虑状态和IL-6水平显着增加。IL-1β和IL-6分别与愤怒和焦虑状态呈正相关。

总之，我们的数据强调了不同的免疫标记在社会认知应激过程中在血浆和唾液中可以类似地检测到。此外，他们可能与不同的情绪反应有关。

原始出处：

La Fratta I, Tatangelo R, et al., The plasmatic and salivary levels of IL-1β, IL-18 and IL-6 are associated to emotional difference during stress in young male. Sci Rep. 2018 Feb 14;8(1):3031. doi: 10.1038/s41598-018-21474-y.

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    2018-10-09 1e145228m78(暂无匿称)

    学习了，谢谢作者分享/

    0

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    2018-03-02 仁心济世

    #心理压力#

    0

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    2018-02-28 orangesking

    好

    0