Int J Cardiol:缺铁影响慢性心衰患者生活质量

2014-04-30 永远 编译 中国医学论坛报CMT心血管微信

一项欧洲多国研究显示,慢性心力衰竭(CHF)患者不论是否贫血,铁缺乏均影响他们的生活质量。论文4月28日在线发表于《国际心脏病学杂志》(Int J Cardiol)。CHF往往合并铁缺乏,但是目前几乎没有关于铁缺乏对CHF患者生活质量影响的研究。该研究纳入1278例CHF患者,患者中位年龄68±12岁,男性患者882例,中位射血分数为38%±15%,,纽约心功能分级Ⅰ~Ⅳ级。研究者评估了铁缺乏对患

一项欧洲多国研究显示,慢性心力衰竭(CHF)患者不论是否贫血,铁缺乏均影响他们的生活质量。论文4月28日在线发表于《国际心脏病学杂志》(Int J Cardiol)。

CHF往往合并铁缺乏,但是目前几乎没有关于铁缺乏对CHF患者生活质量影响的研究。该研究纳入1278例CHF患者,患者中位年龄68±12岁,男性患者882例,中位射血分数为38%±15%,,纽约心功能分级Ⅰ~Ⅳ级。研究者评估了铁缺乏对患者生活质量的影响以及铁缺乏与贫血状态及生活质量的相互作用,并通过明尼苏达心力衰竭生活质量调查问卷(MLHFQ)评估生活质量。

结果显示,未校正的MLHFQ总评分(评分越高,生活质量越差)在铁缺乏和贫血患者中较高(铁缺乏者42±25对非铁缺乏者37±25,P=0.001;贫血者46±25对非贫血者37±25,P<0.001)。多变量回归分析显示,铁缺乏与CHF患者生活质量下降相关,而贫血与CHF患者生活质量下降无关。

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