Obstet Gynecol:肥胖的经产妇女性尝试顺产可以降低新生儿发病率

2015-10-20 Mechront 译 MedSci原创

研究者对47,372名可经阴道分娩的肥胖女性(BMI≥30)进行了回顾性研究,纳入的研究对象均在满月后(≥37周)分娩单胎活产婴儿。前次剖宫产、先天性畸形、死胎等排除在外。研究者分析了不同分娩方式的母儿结局,以及按产次对研究对象进行分层分析。孕产妇结局指标包括:重症监护、死亡、出血、输血或血栓栓塞。新生儿结局指标有:重症监护、死亡、癫痫发作、使用呼吸机、产伤或窒息。研究者通过泊松回归分析数据。研究

研究者对47,372名可经阴道分娩的肥胖女性(BMI≥30)进行了回顾性研究,纳入的研究对象均在满月后(≥37周)分娩单胎活产婴儿。前次剖宫产、先天性畸形、死胎等排除在外。研究者分析了不同分娩方式的母亲和新生儿的结局,以及按产次对研究对象进行分层分析。孕产妇结局指标包括:重症监护、死亡、出血、输血或血栓栓塞。新生儿结局指标有:重症监护、死亡、癫痫发作、使用呼吸机、产伤或窒息。研究者通过泊松回归分析数据。



研究结果显示,15,268名尝试阴道分娩的初产妇,其成功率为 72.6% ,对于23,426名尝试经阴道分娩的经产妇,成功率为93.7%。对于初产妇,孕产妇的不良结局在尝试阴道分娩与计划性剖腹产组间,发生率无显著差异(7.7% vs 4.2% [sRR 1.58, 95% CI 0.96-2.59]) ,但是对于经产妇,该差异显著 (7.6% vs 2.5% [aRR 2.45, 95% CI 1.23-4.9)])。

新生儿不良结局发生率则刚刚相反,经产妇尝试阴道分娩,其婴儿不良结局更少(6.0% vs 11.6% [aRR 0.65, 95% CI 0.51-0.83]),但是在初产妇组该结论不成立 (10.2% vs 12.4% [aRR 0.91, 95% CI 0.74-1.12]) 。

研究结果表明,肥胖初产妇尝试阴道分娩并不会增加母儿不良反应发生率或发病率。但是对于肥胖的经产妇,尝试阴道分娩会增加孕产妇发病率,但是可以降低新生儿发病率。

原始出处:

Clark-Ganheart CA, Reddy UM,et al.Pregnancy Outcomes Among Obese Women and Their Offspring by Attempted Mode of Delivery.Obstet Gynecol. 2015 Oct 5.
 

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    2016-08-31 yhy100200
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    2015-12-27 lifestar

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