Int Urogynecol J:膀胱过度活动综合症中,经皮胫神经刺激(PTNS)成功预测因子研究

2018-12-16 AlexYang MedSci原创

许多研究阐释了经皮胫神经刺激(PTNS)在膀胱过度活动综合症(OAB)中的治疗效果。然而,与成功治疗相关的患者特性没有很好阐释。最近,有研究人员鉴定了成功PTNS治疗的预后因子。研究包括了162名平均年龄为72.7±?11.3,BMI为28.5?±?7.1的女性。研究发现,在治疗后,所有3种OAB症状均有统计学显著性改善。多变量分析阐释了焦虑和抑郁历史与主观的改善相关,然而,主观改善的减少与高血压

许多研究阐释了经皮胫神经刺激(PTNS)在膀胱过度活动综合症(OAB)中的治疗效果。然而,与成功治疗相关的患者特性没有很好阐释。最近,有研究人员鉴定了成功PTNS治疗的预后因子。

研究包括了162名平均年龄为72.7±11.3,BMI为28.5±7.1的女性。研究发现,在治疗后,所有3种OAB症状均有统计学显著性改善。多变量分析阐释了焦虑和抑郁历史与主观的改善相关,然而,主观改善的减少与高血压、先前膀胱内注射脑钠毒素A和骶神经调节相关。然而,将患者根据改善程度< 50%或者≥ 50%来分成2组的话,抑郁/焦虑、尿动力学容积第一感觉空洞和更加严重的基线尿急尿失禁严重度均是主观改善的显著预测因子。

最后,研究人员指出,在难治性OAB中接受PTNS治疗的女性中,抑郁/焦虑历史和基线尿急尿失禁严重度均是成功PTNS结果的阳性预测因子。

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    2018-12-17 一个字-牛

    学习了谢谢分享

    0

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