Cancer Prev Res:喝绿茶增加还是减少前列腺癌风险?

2015-08-08 MedSci MedSci原创

英国格拉斯哥大学研究人员对6000多名男性进行长达37年的研究显示,每天喝7杯茶以上的人患前列腺癌的风险比每天喝3杯茶以下的人增加50%。他们的研究结果与先前研究称喝茶可降低患癌、心脏病、糖尿病以及帕金森病的风险相反。不过,最新一项由Kumar NB发表的随机对照研究则证明绿茶儿茶酚使用一年,并不降低前列腺癌的风险。这项研究采用安慰剂对照,而绿茶儿茶酚混合物包括400mg 儿茶素(EGCG),每天

英国格拉斯哥大学研究人员对6000多名男性进行长达37年的研究显示,每天喝7杯茶以上的人患前列腺癌的风险比每天喝3杯茶以下的人增加50%。他们的研究结果与先前研究称喝茶可降低患癌、心脏病、糖尿病以及帕金森病的风险相反。


不过,最新一项由Kumar NB发表的随机对照研究则证明绿茶儿茶酚使用一年,并不降低前列腺癌的风险。这项研究采用安慰剂对照,而绿茶儿茶酚混合物包括400mg 儿茶素(EGCG),每天使用,持续1年,但是,与安慰剂相比,并没有降低前列腺癌的风险。

还有一些研究则认为绿茶本身对前列腺癌作用可能并不大,但却可以增强化疗药的作用。

Cup of tea

卡什夫·沙菲克(Kashif Shafique)博士从1970年开始这项研究,参与者当时在21到75岁之间,被要求完成饮茶、咖啡以及酒量的调查问卷,当然也包括吸烟习惯和健康状 况。当时6016人中,只有不到1/4的人每天喝茶7杯以上。这些人在随后37年中,有6.4%患上前列腺癌。

研究人员发现,喝大量茶的人通常完全戒酒,而且生活方式更为健康,也可能因为活得时间更长,所以患前列腺癌的几率更大。沙菲克说:“我们还不清楚是茶叶本身含有危险因素,亦或是饮茶者通常更健康和更长寿,因此患前列腺癌更普遍。”

据悉,英国几乎80%的人都喝茶,每天消费茶1.65亿杯。英国茶叶每年价值超过7亿英镑(约合人民币70亿元)。而英国每年有4万人患前列腺癌,超过1万名患者死亡.

同时,Kashif Shafique博士还发现,饮咖啡可以降低前列腺癌风险,与绿茶作用相反。

总之,茶叶对前列腺癌的影响还存在争议,后续可能还需要更大样本,更长期,设计更严谨的研究来证实。

原始出处:

Kumar NB, Pow-Sang J, Egan KM, Spiess PE, Dickinson S, Salup R, Helal M, McLarty JW, Williams CR, Schreiber F Medical Oncology, Parnes HL, Sebti S, Kazi A, Kang L, Quinn GP, Smith T, Yue B, Diaz K, Chornokur G, Crocker T, Schell MJ.Randomized, Placebo-Controlled Trial of Green Tea Catechins for Prostate Cancer Prevention. Cancer Prev Res (Phila). 2015 Apr 14. pii: canprevres.0324.2014

Shafique K, McLoone P, Qureshi K, Leung H, Hart C, Morrison DS.Tea consumption and the risk of overall and grade specific prostate cancer: a large prospective cohort study of Scottish men. Nutr Cancer. 2012 Aug;64(6):790-7.

Shafique K, McLoone P, Qureshi K, Leung H, Hart C, Morrison DS.Coffee consumption and prostate cancer risk: further evidence for inverse relationship. Nutr J. 2012 Jun 13;11:42

Wang P, Henning SM, Heber D, Vadgama JV.Sensitization to docetaxel in prostate cancer cells by green tea and quercetin. J Nutr Biochem. 2015 Apr;26(4):408-15

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    2015-10-16 sjq027
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    2015-11-01 桥断梅边

    有用

    0

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  4. [GetPortalCommentsPageByObjectIdResponse(id=2061472, encodeId=4b5e20614e273, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Fri Oct 16 23:01:00 CST 2015, time=2015-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42116, encodeId=453942116ba, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2d1658827, createdName=桥断梅边, createdTime=Sun Nov 01 09:38:00 CST 2015, time=2015-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2022547, encodeId=b3d4202254e8a, content=<a href='/topic/show?id=42b532553af' target=_blank style='color:#2F92EE;'>#前列腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32553, encryptionId=42b532553af, topicName=前列腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d2f42500210, createdName=12498ef1m31(暂无昵称), createdTime=Tue Feb 16 00:01:00 CST 2016, time=2016-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35394, encodeId=495935394e2, content=太多的干扰了, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=126b110623, createdName=ndd99, createdTime=Mon Aug 10 21:17:00 CST 2015, time=2015-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35348, encodeId=058535348f5, content=有可能是绿茶对不同肿瘤作用是不一样的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Mon Aug 10 03:45:00 CST 2015, time=2015-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35329, encodeId=f4fc3532923, content=但是这和茶的浓度关系呢!?, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sun Aug 09 21:21:00 CST 2015, time=2015-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402285, encodeId=e6a2140228538, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun Aug 09 19:01:00 CST 2015, time=2015-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35287, encodeId=10123528e63, content=哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Sat Aug 08 15:03:00 CST 2015, time=2015-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35278, encodeId=d658352e83c, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sat Aug 08 09:45:00 CST 2015, time=2015-08-08, status=1, ipAttribution=)]
    2015-08-10 ndd99

    太多的干扰了

    0

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    2015-08-10 lovetcm

    有可能是绿茶对不同肿瘤作用是不一样的。

    0

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    2015-08-09 lecoo

    但是这和茶的浓度关系呢!?

    0

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    2015-08-09 hbwxf
  8. [GetPortalCommentsPageByObjectIdResponse(id=2061472, encodeId=4b5e20614e273, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Fri Oct 16 23:01:00 CST 2015, time=2015-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42116, encodeId=453942116ba, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1b2d1658827, createdName=桥断梅边, createdTime=Sun Nov 01 09:38:00 CST 2015, time=2015-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2022547, encodeId=b3d4202254e8a, content=<a href='/topic/show?id=42b532553af' target=_blank style='color:#2F92EE;'>#前列腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32553, encryptionId=42b532553af, topicName=前列腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d2f42500210, createdName=12498ef1m31(暂无昵称), createdTime=Tue Feb 16 00:01:00 CST 2016, time=2016-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35394, encodeId=495935394e2, content=太多的干扰了, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=126b110623, createdName=ndd99, createdTime=Mon Aug 10 21:17:00 CST 2015, time=2015-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35348, encodeId=058535348f5, content=有可能是绿茶对不同肿瘤作用是不一样的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Mon Aug 10 03:45:00 CST 2015, time=2015-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35329, encodeId=f4fc3532923, content=但是这和茶的浓度关系呢!?, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1ab1619415, createdName=lecoo, createdTime=Sun Aug 09 21:21:00 CST 2015, time=2015-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402285, encodeId=e6a2140228538, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sun Aug 09 19:01:00 CST 2015, time=2015-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35287, encodeId=10123528e63, content=哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Sat Aug 08 15:03:00 CST 2015, time=2015-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=35278, encodeId=d658352e83c, content=有趣, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sat Aug 08 09:45:00 CST 2015, time=2015-08-08, status=1, ipAttribution=)]
    2015-08-08 dearluodi

    哈哈

    0

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    2015-08-08 stupidox

    有趣

    0

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